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  2. SGLT2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/SGLT2_inhibitor

    Dapagliflozin is an example of an SGLT-2 inhibitor, it is a competitive, highly selective inhibitor of SGLT. It acts via selective and potent inhibition of SGLT-2, and its activity is based on each patient's underlying blood sugar control and kidney function. The results are decreased kidney reabsorption of glucose, glucosuria effect increases ...

  3. Sodium-glucose transport proteins - Wikipedia

    en.wikipedia.org/wiki/Sodium-glucose_transport...

    [2] [3] SGLT1, encoded by the SLC5A1 gene, is primarily expressed in the late proximal tubule (S3 segment) and accounts for the remaining 3% of glucose reabsorption. [2] [3] In addition to SGLT1 and SGLT2, there are 10 other members in the human protein family SLC5A. [4] SLC5A4, also known as SGLT3, is a member of the sodium-glucose ...

  4. Sodium/glucose cotransporter 2 - Wikipedia

    en.wikipedia.org/wiki/Sodium/glucose_cotransporter_2

    SGLT2 is a member of the sodium glucose cotransporter family, which are sodium-dependent glucose transport proteins. SGLT2 is the major cotransporter involved in glucose reabsorption in the kidney. [6] SGLT2 is located in the early proximal tubule, and is responsible for reabsorption of 80-90% of the glucose filtered by the kidney glomerulus. [7]

  5. 30 Christmas Traditions From Around the World - AOL

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    <i>Caga Tiós</i> on display at the Santa Llúcia Christmas market in Barcelona in 2006. Credit - Greg Gladman—Flickr. C hristmas is one of the most globally celebrated holidays in the world ...

  6. Kia recalls over 62,000 vehicles: See affected models - AOL

    www.aol.com/kia-recalls-over-62-000-175650685.html

    Kia is recalling over 62,000 of its 2022-2024 EV6 vehicles. The automobile manufacturer is recalling 62,872 cars for a loss of drive power from a damaged charging unit.

  7. Parents Accused of Leaving Toddler in Closet Overnight with ...

    www.aol.com/parents-accused-leaving-toddler...

    The 2-year-old girl's body temperature was found to be as high as 109.4 degrees Fahrenheit, according to police Parents Accused of Leaving Toddler in Closet Overnight with Space Heater On. She Was ...

  8. Sodium/glucose cotransporter 1 - Wikipedia

    en.wikipedia.org/wiki/Sodium/glucose_cotransporter_1

    Sodium/glucose cotransporter 1 (SGLT1) also known as solute carrier family 5 member 1 is a protein in humans that is encoded by the SLC5A1 gene [4] [5] which encodes the production of the SGLT1 protein to line the absorptive cells in the small intestine and the epithelial cells of the kidney tubules of the nephron for the purpose of glucose uptake into cells. [6]

  9. ATC code A10 - Wikipedia

    en.wikipedia.org/wiki/ATC_code_A10

    ATC code A10 Drugs used in diabetes is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.

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