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The disadvantage of fomepizole is that it is expensive. Costing US$1,000 per gram, an average course used in an adult poisoning would cost approximately $3,500 to $4,000. [39] [40] Despite the cost, fomepizole is gradually replacing ethanol as the antidote of choice in ethylene glycol poisoning. [37] [38]
The 1985 Austrian diethylene glycol wine scandal (German: Glykolwein-Skandal) was an incident in which several Austrian wineries illegally adulterated their wines using the toxic substance diethylene glycol (a minor ingredient in some brands of antifreeze) to make the wines taste sweeter and more full-bodied in the style of late harvest wines. [1]
The U.S. Code of Federal Regulations allows no more than 0.2% of diethylene glycol in polyethylene glycol when the latter is used as a food additive. [11] In Australia , it is only allowed at less than 0.25% w/w of DEG as an impurity in polyethylene glycol (PEG), [ 12 ] even in toothpaste.
Bitterants are used in antifreeze to prevent pet and child poisonings. [1] It is required by law in some places (France, Oregon, etc.). Gas dusters often use a bitterant to discourage inhalant abuse, although this can cause problems for legitimate users. The bitterant not only leaves a bitter flavor in the air, but also leaves a bitter residue ...
The World Health Organization (WHO) names four toxicity classes: . Class I – a: extremely hazardous; Class I – b: highly hazardous; Class II: moderately hazardous; Class III: slightly hazardous
Since the 1990s, several mass poisonings from toxic cough syrup have occurred in developing countries. In these cases, an ingredient in cough syrup, glycerine (glycerol), was replaced with diethylene glycol, a cheaper alternative to glycerine for industrial applications.
Celebrate Groundhog Day with this collection of funny Groundhog Day jokes and corny puns that'll have kids, adults and the rest of the family in stitches. 36 Groundhog Day jokes that are ...
Ethylene glycol, antifreeze, is extremely toxic to dogs. It has a sweet taste and thus dogs will drink it. As little as 2 1/2 tablespoons can kill a medium-sized dog in 2–3 days. This type of poisoning is often fatal as dog owners do not know their pet has ingested the antifreeze. De-icing fluids can also contain ethylene glycol.