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  2. Hammett equation - Wikipedia

    en.wikipedia.org/wiki/Hammett_equation

    Consider para-disubstituted benzene p-F-C 6 H 4-Z, where Z is a substituent such as NH 2, NO 2, etc. The fluorine atom is para with respect to the substituent Z in the benzene ring. The image on the right shows four distinguished ring carbon atoms, C1, C2, C3, C4 in p-F-C 6 H 4-Z molecule. The carbon with Z is defined as C1(ipso) and ...

  3. Nucleophilic aromatic substitution - Wikipedia

    en.wikipedia.org/wiki/Nucleophilic_aromatic...

    The mechanism of S N 2 reaction does not occur due to steric hindrance of the benzene ring. In order to attack the C atom, the nucleophile must approach in line with the C-LG (leaving group) bond from the back, where the benzene ring lies. It follows the general rule for which S N 2 reactions occur only at a tetrahedral carbon atom.

  4. Reduction of nitro compounds - Wikipedia

    en.wikipedia.org/wiki/Reduction_of_nitro_compounds

    The reduction of nitro compounds are chemical reactions of wide interest in organic chemistry. The conversion can be effected by many reagents. The conversion can be effected by many reagents. The nitro group was one of the first functional groups to be reduced .

  5. Nitro compound - Wikipedia

    en.wikipedia.org/wiki/Nitro_compound

    The structure of an organic nitro compound. In organic chemistry, nitro compounds are organic compounds that contain one or more nitro functional groups (−NO 2). The nitro group is one of the most common explosophores (functional group that makes a compound explosive) used globally. The nitro group is also strongly electron-withdrawing.

  6. Electrophilic aromatic directing groups - Wikipedia

    en.wikipedia.org/wiki/Electrophilic_aromatic...

    Diagram showing the ortho, meta and para positions relative to a substituent X on a benzene ring. Electron donating groups are typically divided into three levels of activating ability (The "extreme" category can be seen as "strong".) Electron withdrawing groups are assigned to similar groupings.

  7. Béchamp reduction - Wikipedia

    en.wikipedia.org/wiki/Béchamp_reduction

    The Béchamp reduction (or Béchamp process) is a chemical reaction that converts aromatic nitro compounds to their corresponding anilines using iron as the reductant: [1] 4 C 6 H 5 NO 2 + 9 Fe + 4 H 2 O → 4 C 6 H 5 NH 2 + 3 Fe 3 O 4. This reaction was once a major route to aniline, but catalytic hydrogenation is the preferred method. [2]

  8. Nitration - Wikipedia

    en.wikipedia.org/wiki/Nitration

    In organic chemistry, nitration is a general class of chemical processes for the introduction of a nitro group (−NO 2) into an organic compound.The term also is applied incorrectly to the different process of forming nitrate esters (−ONO 2) between alcohols and nitric acid (as occurs in the synthesis of nitroglycerin).

  9. Ortho effect - Wikipedia

    en.wikipedia.org/wiki/Ortho_effect

    This is caused by steric effects and bonding interactions along with polar effects caused by the various substituents which are in a given molecule, resulting in changes in its chemical and physical properties. The ortho effect is associated with substituted benzene compounds. There are three main ortho effects in substituted benzene compounds: