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Combining early concepts derived from the specificity theory and the peripheral pattern theory, the gate control theory is considered to be one of the most influential theories of pain. This theory provided a neural basis which reconciled the specificity and pattern theories -- and ultimately revolutionized pain research.
Ronald Melzack OC OQ FRSC (July 19, 1929 – December 22, 2019) was a Canadian psychologist and professor of psychology at McGill University. [1] [2] In 1965, he and Patrick David Wall re-charged pain research by introducing the gate control theory of pain.
Wall & Melzack's Textbook of Pain is a medical textbook published by Elsevier. It is named after Patrick David Wall and Ronald Melzack, who introduced the gate control theory into pain research in the 1960s. First released in 1984, the book has been described as "the most comprehensive scientific reference text in the field of pain medicine". [1]
At Melzack's urging they wrote a paper on the Gate control theory of pain and published it in Brain in 1962; according to Wall it was read by around three people. After expanding and rewriting the article they republished it as Pain Mechanisms: a new theory in Science in 1965 where it drew wider attention, with mostly negative comments. [11]
Ronald Melzack and Patrick Wall introduced their "gate control" theory of pain in the 1965 Science article "Pain Mechanisms: A New Theory". [17]
The McGill Pain Questionnaire, also known as McGill Pain Index, is a scale of rating pain developed at McGill University by Melzack and Torgerson in 1971. [1] It is a self-report questionnaire that allows individuals to give their doctor a good description of the quality and intensity of pain that they are experiencing.
Pain motivates organisms to withdraw from damaging situations, to protect a damaged body part while it heals, and to avoid similar experiences in the future. [2] Most pain resolves once the noxious stimulus is removed and the body has healed, but it may persist despite removal of the stimulus and apparent healing of the body. Sometimes pain ...
Synaptic gating is the ability of neural circuits to gate inputs by either suppressing or facilitating specific synaptic activity. Selective inhibition of certain synapses has been studied thoroughly (see Gate theory of pain), and recent studies have supported the existence of permissively gated synaptic transmission. In general, synaptic ...