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2. Stiff-person syndrome - Wikipedia

   en.wikipedia.org/wiki/Stiff-person_syndrome

   Stiff-person syndrome (SPS), also known as stiff-man syndrome, [1] is a rare neurological disorder of unclear cause characterized by progressive muscular rigidity and stiffness. The stiffness primarily affects the truncal muscles and is characterised by spasms , resulting in postural deformities.

3. What is stiff-person syndrome? Celine Dion sings live for the ...

   www.aol.com/lifestyle/know-stiff-person-syndrome...

   Celine Dion took to the stage for the first time since revealing her stiff-person syndrome diagnosis in September 2022. Wearing a white gown, with the rain beating down and the Eiffel Tower in the ...

4. Celine Dion Opens Up About Living with Stiff Person Syndrome

   www.aol.com/lifestyle/celine-dion-opens-living...

   Céline Dion is speaking out about stiff person syndrome (SPS), a diagnosis she first revealed nearly two years ago. SPS is a rare autoimmune neurological disease that affects muscles and ...

5. Céline Dion suffers 'unimaginable' medical crisis on camera ...

   www.aol.com/news/c-line-dion-suffers...

   Many patients with stiff person syndrome experience muscle cramping, spasms and stiffness constantly, but certain movements or emotions can trigger "a complete, whole-body spasm," Piquet, who is a ...

6. Celine Dion's Documentary About Stiff Person Syndrome ... - AOL

   www.aol.com/entertainment/celine-dions...

   Stiff person syndrome, which occurs in about one in 1 million people, is characterized by progressive muscle rigidity which leads to impaired mobility, muscle spasms, postural deformities and ...

7. Hyoscine butylbromide - Wikipedia

   en.wikipedia.org/wiki/Hyoscine_butylbromide

   Hyoscine butylbromide, also known as scopolamine butylbromide [4] and sold under the brandname Buscopan among others, [5] is an anticholinergic medication used to treat abdominal pain, esophageal spasms, bladder spasms, biliary colic, [6] and renal colic. [7] [8] It is also used to improve excessive respiratory secretions at the end of life. [9]

8. Celine Dion Has Stiff-Person Syndrome. Here's What That ... - AOL

   www.aol.com/celine-dion-stiff-person-syndrome...

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9. Glutamate decarboxylase - Wikipedia

   en.wikipedia.org/wiki/Glutamate_decarboxylase

   High titers of autoantibodies to glutamic acid decarboxylase (GAD) are well documented in association with stiff person syndrome (SPS). [35] Glutamic acid decarboxylase is the rate-limiting enzyme in the synthesis of γ-aminobutyric acid (GABA), and impaired function of GABAergic neurons has been implicated in the pathogenesis of SPS.