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Naltrexone/bupropion, sold under the brand name Contrave among others, is a fixed-dose combination medication for the management of chronic obesity in adults in combination with a reduced-calorie diet and increased physical activity. [4] [6] It contains naltrexone, an opioid antagonist, and bupropion, an aminoketone atypical antidepressant. [4]
(Related: Weight Loss Workout Plan for Women to Reach Your Goals) ... Contrave: This is a combination of bupropion (an antidepressant and aid to quit smoking) and naltrexone (used for alcohol and ...
Alternatively, switching from a more modern type of antidepressant, such as an SSRI or SNRI, to an antidepressant for weight loss, such as bupropion, may also produce improvements.
Naltrexone-bupropion. An FDA-approved weight loss medication, ... This is a combination of an appetite suppressant called phentermine and an anticonvulsant called topiramate.
Bupropion, when used for treating long-term weight gain over six to twelve months, results in an average weight loss of 2.7 kilograms (6.0 lb) over placebo. [74] This is not much different from the weight loss produced by several other weight-loss medications such as sibutramine or orlistat . [ 74 ]
Bupropion/zonisamide (former tentative brand name Empatic, Excalia) is an experimental combination of bupropion which was under development for the treatment of obesity. [1] [2] [3] Bupropion is a norepinephrine–dopamine reuptake inhibitor and nicotinic acetylcholine receptor antagonist, while zonisamide is an anticonvulsant acting as a sodium channel blocker, T-type calcium channel blocker ...
Weight loss medications like Contrave (a combination of naltrexone and bupropion) block the reward pathways that make it tempting to binge eat, but there are side effects.
Creating a calorie deficit is a factor in most weight loss strategies, whether through changes in nutrition, increasing daily activity or a combination of both. There are healthy ways to approach ...
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