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  2. Lokivetmab - Wikipedia

    en.wikipedia.org/wiki/Lokivetmab

    Lokivetmab, trade name Cytopoint, is a monoclonal antibody used to treat atopic dermatitis in dogs. [1] It acts against interleukin 31 (IL-31), [2] which is a cytokine involved in causing itchiness (pruritus). [2] Lokivetmab is administered by subcutaneous injection; each dose is effective for four to eight weeks. [3]

  3. Oclacitinib - Wikipedia

    en.wikipedia.org/wiki/Oclacitinib

    Normally, a cytokine binds to a JAK (Janus kinase) receptor, driving the two individual chains to come together and self-phosphorylate. This brings in STAT proteins , which are activated and then go to the nucleus to increase transcription of genes coding for cytokines, thus increasing cytokine production.

  4. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    Cytopoint [90] mab: veterinary: Canis lupus familiaris IL31: Y: clinical signs of atopic dermatitis in dogs [90] Lorvotuzumab mertansine: mab: humanized: CD56: cancer Lucatumumab [13] mab: human: CD40: multiple myeloma, non-Hodgkin's lymphoma, Hodgkin's lymphoma: Lulizumab pegol [6] mab: humanized: CD28: autoimmune diseases Lumiliximab [9] mab ...

  5. Seviteronel - Wikipedia

    en.wikipedia.org/wiki/Seviteronel

    Seviteronel (developmental codes VT-464 and, formerly, INO-464) is an experimental cancer medication which is under development by Viamet Pharmaceuticals and Innocrin Pharmaceuticals for the treatment of prostate cancer and breast cancer. [1]

  6. Video of Abused Foster Dog Living All Her ‘Firsts’ Goes Viral

    www.aol.com/lifestyle/video-abused-foster-dog...

    The video’s caption gives us an introduction to the dog’s traumatic past. When she was brought to the shelter in 2023, her body bore the physical scars of abuse, and her spirit was marked by fear.

  7. CHOP (chemotherapy) - Wikipedia

    en.wikipedia.org/wiki/CHOP_(chemotherapy)

    The combination is then referred to as COP (cyclophosphamide, Oncovin, and prednisone or prednisolone) or CVP (cyclophosphamide, vincristine, and prednisone or prednisolone). As elderly patients have a greater risk of toxicity from the drugs, an option is to use an attenuated drug regimen, called miniCHOP.

  8. Watch 'The Voice' 4-Chair Turn That Michael Bublé Says Has a ...

    www.aol.com/watch-voice-4-chair-turn-030954000.html

    Night 3 of Season 27’s Blind Auditions on The Voice had not one, but two four-chair turns. The second being BDii (Brian Darden II), 31, originally from Hampton, VA now of Atlanta, GA, who closed ...

  9. Jack Nicholson Makes Rare TV Appearance at ‘SNL50 ...

    www.aol.com/entertainment/jack-nicholson-makes...

    Jack Nicholson Makes Rare TV Appearance at ‘SNL50,’ Introduces Adam Sandler’s Heartfelt Song Honoring the Show’s History