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Pseudobulbar affect (PBA), or emotional incontinence, is a type of neurological disorder characterized by uncontrollable episodes of crying or laughing. PBA occurs secondary to a neurologic disorder or brain injury. Patients may find themselves crying uncontrollably at something that is only slightly sad, being unable to stop themselves for ...
Since pseudobulbar palsy is a syndrome associated with other diseases, treating the underlying disease may eventually reduce the symptoms of pseudobulbar palsy. [ citation needed ] Possible pharmacological interventions for pseudobulbar affect include the tricyclic antidepressants , serotonin reuptake inhibitors , and a novel approach utilizing ...
Emotional disturbance (e.g. pseudobulbar affect) and cognitive and behavioural changes (e.g. problems in word fluency, decision-making, and memory) are also seen. [ 2 ] [ 6 ] There can be lower motor neuron findings (e.g. muscle wasting, muscle twitching), upper motor neuron findings (e.g. brisk reflexes, Babinski reflex , Hoffman's reflex ...
Avanir Pharmaceuticals (NAS: AVNR) is a biotechnology company developing therapies focused on the central nervous system. ... Nuedexta, for the treatment of pseudobulbar affect. Skip to main ...
In medicine and psychology, emotional lability is a sign or symptom typified by exaggerated changes in mood or affect in quick succession. [1] [2] Sometimes the emotions expressed outwardly are very different from how the person feels on the inside. These strong emotions can be a disproportionate response to something that happened, but other ...
Download as PDF; Printable version; ... is a fixed-dose combination medication for the treatment of pseudobulbar affect ... and is marketed by Avanir Pharmaceuticals. [4]
A medical sign is an objective observable indication of a disease, injury, or medical condition that may be detected during a physical examination. [7] These signs may be visible, such as a rash or bruise, or otherwise detectable such as by using a stethoscope or taking blood pressure.
Hi there, I think "labile affect" is referring quite specifically to the neurological manifestation which either occurs without stimuli or is much more exaggerated than one would normally expect. By contrast, tearfulness during depression or bereavement is a perfectly normal symptom and so isn't really pathological in the way that labile affect is.