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Borna disease, also known as sad horse disease, [1] is an infectious neurological syndrome [2] of warm-blooded animals, caused by Borna disease viruses 1 and 2 (BoDV-1/2). BoDV-1/2 are neurotropic viruses of the species Mammalian 1 orthobornavirus, and members of the Bornaviridae family within the Mononegavirales order.
P24 is encoded by open reading frame II (ORF-II) and undergoes high rates of mutation in humans. It [binds amphoterin-HMGB1, a multifunctional protein, directly and may cause deleterious effects in cellular functions by interference with HMGB1. [5] Horse and human P24 have no species-specific amino acid residues, suggesting that the two viruses ...
Covering sickness, or dourine (French, from the Arabic darina, meaning mangy (said of a female camel), feminine of darin, meaning dirty), [1] is a disease of horses and other members of the family Equidae. The disease is caused by Trypanosoma equiperdum, which belongs to an important genus of parasitic protozoa. [2]
Horses cannot pass the disease among themselves; that is, one horse cannot contract the disease from another infected horse. The horse is a dead-end, or aberrant, host of the parasite. Although all horses are believed to be susceptible to EPM the disease is usually found in younger horses typically around three to six years of age. [ 2 ]
Vertebrates, including mammals and humans, and arthropods serve as natural hosts. There are 12 species in this genus. Diseases associated with this genus include smallpox, cowpox, horsepox, camelpox, and mpox. [1] [2] The most widely known member of the genus is Variola virus, which causes smallpox.
DENVER (Reuters) -An unknown and highly contagious disease has killed 85 wild horses in less than a week at a federal corral in Colorado, officials said on Wednesday, revising the number upward ...
[2] [14] [16] Madariaga virus was first identified in 1936 from a horse in Argentina. [14] The first human cases were identified in 1938 in Massachusetts, during an outbreak with 38 human cases and 248 horse cases. [1] 25 of the 38 human cases resulted in death. That same year, an epizootic occurred in Connecticut and Rhode Island and involved ...
The threat of so-called “mad cow disease” has all but faded from the collective memory, after its appearance in U.K. cattle in 1986. Human deaths from the scourge, caused by eating ...