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Senile pruritus is one of the most common conditions in the elderly or people over 65 years of age with an emerging itch that may be accompanied with changes in temperature and textural characteristics. [1] [2] [3] In the elderly, xerosis, is the most common cause for an itch due to the degradation of the skin barrier over time. [4]
[1] [2] Patients observe these symptoms and seek medical advice from healthcare professionals. Because most people are not diagnostically trained or knowledgeable, they typically describe their symptoms in layman's terms, rather than using specific medical terminology.
Friability testing is a laboratory technique used by the pharmaceutical industry to test the durability of tablets during transit. This testing involves repeatedly dropping a sample of tablets over a fixed time, using a rotating wheel with a baffle.
A study that compared HGPS patient cells with the skin cells from young and elderly normal human subjects found similar defects in the HGPS and elderly cells, including down-regulation of certain nuclear proteins, increased DNA damage, and demethylation of histone, leading to reduced heterochromatin. [39]
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
Malnutrition and poor nutritional status is an area of concern, affecting 12% to 50% of hospitalized elderly patients and 23% to 50% of institutionalized elderly patients living in long-term care facilities such as assisted living communities and skilled nursing facilities. [20]
The geriatric rheumatology clinic provides evaluation and management services to patients with various musculoskeletal and soft tissue disorders.Evaluation of the elderly patient is often complex due to the many comorbid conditions encountered in this population often compounded by cognitive disorders, functional decline, polypharmacy and limited social supports.
Chronic wound exudate contains proteolytic enzymes and other components that degrade skin integrity and predispose it to inflammation. [8] [9] Moisture-associated skin damage can also be caused by bodily fluids or other contaminants that enter the periwound areas, for example, in patients with urinary or fecal incontinence, or colostomy ...