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There are two kinds of neurons involved in the transmission of any signal through the sympathetic system: pre-ganglionic and post-ganglionic. The shorter preganglionic neurons originate in the thoracolumbar division of the spinal cord specifically at T1 to L2~L3, and travel to a ganglion, often one of the paravertebral ganglia, where they synapse with a postganglionic neuron.
The general rule of interaction of the nerve fibers in the sympathetic nervous system begins at the spinal cord. Here they arise from the thoracolumbar (T1–L2) regions' lateral horn of grey and emerge via the ventral root. They enter their respective spinal nerve (e.g. T5), and thus enter the white ramus communicans. This myelinated division ...
The four main divisions of the spinal column, from top to bottom: cervical, thoracic, lumbar, and sacral. The lateral grey column (lateral column, lateral cornu, lateral horn of spinal cord, intermediolateral column) is one of the three grey columns of the spinal cord (which give the shape of a butterfly); the others being the anterior and posterior grey columns.
The sympathetic division emerges from the spinal cord in the thoracic and lumbar areas, terminating around L2-3. The parasympathetic division has craniosacral "outflow", meaning that the neurons begin at the cranial nerves (specifically the oculomotor nerve, facial nerve, glossopharyngeal nerve and vagus nerve) and sacral (S2-S4) spinal cord.
The division of the autonomic nervous system into sympathetic and parasympathetic pathways is particularly useful from a medical treatment perspective [source]. Jänig et al. warn that changing the classifications of the systems could result in confusion on how to treat some disease, particularly those of the gut and stomach region. [9]
The sympathetic trunk is a fundamental part of the sympathetic nervous system, and part of the autonomic nervous system. It allows nerve fibres to travel to spinal nerves that are superior and inferior to the one in which they originated. Also, a number of nerves, such as most of the splanchnic nerves, arise directly from the trunks.
The superior mesenteric ganglion is the synapsing point for one of the pre- and post-synaptic nerves of the sympathetic division of the autonomic nervous system. Specifically, contributions to the superior mesenteric ganglion arise from the lesser splanchnic nerve , which typically arises from the spinal nerve roots of T10 and T11 . [ 1 ]
Another major difference between the two ANS (autonomic nervous systems) is divergence. Whereas in the parasympathetic division there is a divergence factor of roughly 1:4, in the sympathetic division there can be a divergence of up to 1:20. This is due to the number of synapses formed by the preganglionic fibers with ganglionic neurons.