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The disease spectrum results from clonal accumulation and proliferation of cells resembling the epidermal dendritic cells called Langerhans cells, sometimes called dendritic cell histiocytosis. These cells in combination with lymphocytes , eosinophils , and normal histiocytes form typical LCH lesions that can be found in almost any organ . [ 5 ]
Chronic multifocal Langerhans cell histiocytosis; Other names: Hand–Schüller–Christian disease: A child with Hand-Schüller-Christian Disease: Specialty: Dermatology: Symptoms: Triad of bulging eyes, breakdown of bone, diabetes insipidus [1] Other symptoms eg. bone pain, facial asymmetry, ear infections, teeth/gum problems, liver and lung ...
8 Autoimmune Diseases That Cause Hair Loss. This article was reviewed by Knox Beasley, MD.. You might associate autoimmune conditions with symptoms like skin disease, chronic pain, and fatigue.
Letterer–Siwe disease, (LSD) or Abt-Letterer-Siwe disease, is one of the four recognized clinical syndromes of Langerhans cell histiocytosis (LCH) and is the most severe form, involving multiple organ systems such as the skin, bone marrow, spleen, liver, and lung. Oral cavity and gastrointestinal involvement may also be seen.
Hair loss treatments like finasteride (a daily pill) and topical minoxidil (treatment used twice daily) stimulate hair growth in areas where hair is more likely to thin or fall out.
In a study with 22 participants (half men, half women), those who got stem cell treatment reported significant increases in hair growth compared to a placebo. But some adverse events were noted ...
Minoxidil, applied topically, is widely used for the treatment of hair loss. It may be effective in helping promote hair growth in both men and women with androgenic alopecia. [20] [21] About 40% of men experience hair regrowth after 3–6 months. [22] It is the only topical product that is FDA approved in America for androgenic hair loss. [20]
Today, the scientific consensus is that finasteride is safe hair loss treatment for most men. A 2019, study involving 10,000 participants found no link between finasteride and an elevated risk of ...