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Human Endogenous Retrovirus-W (HERV-W) is a family of Human Endogenous Retroviruses (HERVs). HERVs are part of a superfamily of repetitive and transposable elements . Transposable elements are sequences of DNA that can move or "jump" around the genome, sometimes replicating and inserting themselves in different locations.
n/a Ensembl ENSG00000242950 n/a UniProt Q9UQF0 n/a RefSeq (mRNA) NM_014590 NM_001130925 n/a RefSeq (protein) NP_001124397 NP_055405 n/a Location (UCSC) Chr 7: 92.47 – 92.48 Mb n/a PubMed search n/a Wikidata View/Edit Human Syncytin-1 also known as enverin is a protein found in humans and other primates that is encoded by the ERVW-1 gene (endogenous retrovirus group W envelope member 1 ...
Dendrogram of various classes of endogenous retroviruses. Endogenous retroviruses (ERVs) are endogenous viral elements in the genome that closely resemble and can be derived from retroviruses. They are abundant in the genomes of jawed vertebrates, and they comprise up to 5–8% of the human genome (lower estimates of ~1%). [1] [2]
A retrovirus is a type of virus that inserts a DNA copy of its RNA genome into the DNA of a host cell that it invades, thus changing the genome of that cell. [2] After invading a host cell's cytoplasm, the virus uses its own reverse transcriptase enzyme to produce DNA from its RNA genome, the reverse of the usual pattern, thus retro (backward).
n/a Ensembl n/a n/a UniProt Q14264 n/a RefSeq (mRNA) NM_001007253 NM_001396062 n/a RefSeq (protein) NP_001007254 n/a Location (UCSC) n/a n/a PubMed search n/a Wikidata View/Edit Human HERV-R_7q21.2 provirus ancestral envelope (Env) polyprotein is a protein that in humans is encoded by the ERV3 gene. Function The human genome includes many retroelements including the human endogenous ...
Syncytin-2 also known as endogenous retrovirus group FRD member 1 is a protein that in humans is encoded by the ERVFRD-1 gene. [5] This protein plays a key role in the implantation of human embryos in the womb. [6] This gene is conserved among all primates, with an estimated age of 45 million years. The receptor for this fusogenic env protein ...
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The group includes all ssRNA-RT viruses (including the retroviruses) and dsDNA-RT viruses. It is the sole class in the phylum Artverviricota, which is the sole phylum in the kingdom Pararnavirae. [2] The name of the group is a portmanteau of "reverse transcriptase" and -viricetes which is the suffix for a virus class. [1]