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Aphthous stomatitis, [2] or recurrent aphthous stomatitis (RAS), commonly referred to as a canker sore or salt blister, is a common condition characterized by the repeated formation of benign and non-contagious mouth ulcers (aphthae) in otherwise healthy individuals.
Diagramatic representation of mucosal erosion (left), excoriation (center), and ulceration (right) Simplistic representation of the life cycle of mouth ulcers. An ulcer (/ ˈ ʌ l s ər /; from Latin ulcus, "ulcer, sore") [2] is a break in the skin or mucous membrane with loss of surface tissue and the disintegration and necrosis of epithelial tissue. [3]
It has likewise been recommended for treatment of inadvertent intra-arterial injections (10 ml of 1% procaine), as it helps relieve pain and vascular spasm. Procaine is an occasional additive in illicit street drugs and is presented and sold usually as cocaine or heroin. [9]
Aphthous stomatitis (canker sores) is the recurrent appearance of mouth ulcers in otherwise healthy individuals. The cause is not completely understood, but it is thought that the condition represents a T cell mediated immune response which is triggered by a variety of factors.
Amlexanox is the active ingredient in a common topical treatment for recurrent aphthous ulcers of the mouth (canker sores), [2] reducing both healing time [3] and pain. [4] Amlexanox 5% paste is well tolerated, [ 5 ] and is typically applied four times per day directly on the ulcers. [ 3 ]
Local anesthesia of oral and pharyngeal mucous membranes (sore throat, cold sores, mouth ulcers, toothache, sore gums, denture irritation) [3] Otic pain (earache) [3] Surgical or procedural local anesthesia [4] Relief of skin pain caused by sunburn, ingrown toenails, hemorrhoids, [5] Examples of combination medications of benzocaine include:
Local anesthetic injections are given in specific areas of the mouth, rather than the whole body. Although several different medications are available, the most commonly used local anesthetic to prevent pain in the area around a tooth is lidocaine (also called xylocaine or lignocaine). Lidocaine's half-life in the body is about 1.5–2 hours. [2]
In the same study, 60 percent of ulcers treated with Debacterol had disappeared by day six compared to about 30 percent in the other treatment groups. [4] Sulfonated phenolics/sulfuric acid appears to be more effective on sores in areas of the mouth that produce less saliva. Since a sore must be dry prior to application of Debacterol, it is ...
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