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U.S. Route 45 crosses the Ohio River between Kentucky and Illinois on the Brookport Bridge. U.S. 45 enters Kentucky at Fulton then northeast past Mayfield then heads directly north into Paducah as a four-lane highway. In Paducah, U.S. 45 serves as a major artery, intersecting with Interstate 24 at exit 7, and intersecting US 60 and 62.
U.S. Route 45 (US 45) in the state of Illinois is a major north–south U.S. Highway that runs from the Brookport Bridge over the Ohio River at Brookport north through rural sections of eastern Illinois and then through the suburbs of Chicago to the Wisconsin state line east of Antioch.
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In the U.S. state of Alabama, U.S. Route 45 (US 45) is a 60-mile-long (97 km) north–south United States Highway in the east south central state of Alabama. It travels from Mobile to the Mississippi state line, just east of State Line, Mississippi. The highway's southern terminus is in Mobile, at an intersection with US 98. Its northern ...
The short elevated section of I-45, which forms the southern boundary of Downtown, is known as the Pierce Elevated after the surface street next to which the freeway runs, while north of I-10 it is known as the North Freeway. I-45 and I-345 in the Dallas area, north of the interchanges with I-20 and SH 310 (old US 75), is the Julius Schepps ...
From the Mississippi state line, US 45 extends north as a four-lane divided highway, running concurrently with unsigned State Route 5 (SR 5), to an intersection with Old US Highway 45 S (a connector to Mississippi Highway 145 [MS 145]), where it narrows to an undivided four-lane and passes through the town of Guys.