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The amygdala, cerebellum, and many other brain regions have been implicated in autism. [15]Unlike some brain disorders which have clear molecular hallmarks that can be observed in every affected individual, such as Alzheimer's disease or Parkinson's disease, autism does not have a unifying mechanism at the molecular, cellular, or systems level.
Iryna Spodarenko / GettyWe’ve come a long way in our understanding of autism since it was first used as a clinical description in 1943. Scientists have identified some of the genes that seem to ...
Human brain in the coronal orientation. Amygdalae are shown in dark red. The amygdala (/ ə ˈ m ɪ ɡ d ə l ə /; pl.: amygdalae / ə ˈ m ɪ ɡ d ə l i,-l aɪ / or amygdalas; also corpus amygdaloideum; Latin from Greek, ἀμυγδαλή, amygdalē, 'almond', 'tonsil' [1]) is a paired nuclear complex present in the cerebral hemispheres of vertebrates.
The following chapters investigate the biological background of autism and how historically it was claimed to be either the result of direct brain damage or poor parenting and how the practice of diagnostic classification, or nosology, negatively impacted the understanding of children with autism and others on the spectrum.
The brain is the central organ of the human nervous system, and with the spinal cord, comprises the central nervous system. It consists of the cerebrum, the brainstem and the cerebellum. The brain controls most of the activities of the body, processing, integrating, and coordinating the information it receives from the sensory nervous system ...
A further example of brain structures relating to ASD is that children with ASD tend to have a larger amygdala, [47] this is another example of being an extreme version of the male brain which generally has a larger amygdala. [4] These brain differences have all been shown to have an influence on social cognition and communication.
Autism, or autism spectrum disorder [a] (ASD), is a neurodevelopmental disorder characterized by repetitive, restricted, and inflexible patterns of behavior, interests, and activities, as well as deficits in social communication and social interaction, and the presence of high or low sensory sensitivity.
Simplified diagram of frontal cortex to striatum to thalamus pathways. There are five defined frontostriatal circuits: motor and oculomotor circuits originating in the frontal eye fields are involved in motor functions; while dorsolateral prefrontal, orbital frontal, and anterior cingulate circuits are involved in executive functions, social behavior and motivational states. [2]