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In children, a ferritin above 10000 μg/L is very sensitive and specific for the diagnosis of HLH, [17] however, the diagnostic utility for ferritin is less for adult HLH patients. [18] The serum fibrinogen level is usually low and the D-dimer level is elevated. [citation needed] The sphingomyelinase is elevated. [19] Bone marrow biopsy shows ...
Delaying initiation of vasopressor therapy during septic shock is associated with increased mortality. [73] Norepinephrine is often used as a first-line treatment for hypotensive septic shock because evidence shows that there is a relative deficiency of vasopressin when shock continues for 24 to 48 hours. [74]
[3] [4] Septic arthritis is an orthopedic emergency, which, if treatment is delayed, can lead to irreversible joint damage. Septic arthritis occurs more often in childhood than at any other time. [4] [5] Kocher criteria are a useful guide to the diagnosis of septic arthritis in children, especially in the hip, one of the most frequently ...
Distributive shock is different from the other three categories of shock in that it occurs even though the output of the heart is at or above a normal level. [2] The most common cause is sepsis leading to a type of distributive shock called septic shock, a condition that can be fatal. [1]
Septic pelvic thrombophlebitis (SPT), also known as suppurative pelvic thrombophlebitis, is a rare postpartum complication which consists of a persistent postpartum fever that is not responsive to broad-spectrum antibiotics, in which pelvic infection leads to infection of the vein wall and intimal damage leading to thrombogenesis in the ovarian veins (left or right, although right is more ...
Septic shock is a result of a systemic response to infection or multiple infectious causes. The precipitating infections that may lead to septic shock if severe enough include but are not limited to appendicitis, pneumonia, bacteremia, diverticulitis, pyelonephritis, meningitis, pancreatitis, necrotizing fasciitis, MRSA and mesenteric ischemia.
Signs of septic shock include fever or hypothermia, petechia, and purpura. Lab tests might show leukocytosis or leukopenia, metabolic acidosis with high lactate, and more. [7] Anaphylactic shock is caused by an allergen and common signs include facial swelling, throat swelling, hives, wheezing, etc. [7]
The early signs and symptoms of septic arthritis in children and adolescents can be confused with limb injury. [5] Among the signs and symptoms of septic arthritis are: acutely swollen, red, painful joint with fever. [9] Kocher criteria have been suggested to predict the diagnosis of septic arthritis in children. [10]