Ads
related to: brains of people with schizophrenia are called the primary factors that contribute
Search results
Results from the WOW.Com Content Network
The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.
Schizophrenia is thought to have a heritable component in some people, but many people who appear to carry schizophrenia-associated genes may not develop the disease. [13] Research has shown that schizophrenia is a polygenic disorder and that genetic vulnerability to schizophrenia is highly multifactorial , caused by the interactions of several ...
Frontal cortex activity will be impaired, when combined with excess DA activity: the basis for the advancement of schizophrenia, but it is also the neurologic mechanism behind many other psychotic diseases as well. However, the genetic component is the primary source of the neurological abnormalities which leave one prone to psychological ...
Primary polydipsia, or excessive fluid intake, is relatively common in people with chronic schizophrenia. [ 232 ] [ 233 ] This may lead to hyponatremia which can be life-threatening. Antipsychotics can lead to a dry mouth , but there are several other factors that may contribute to the disorder; it may reduce life expectancy by 13 percent. [ 233 ]
Risk factors for mental illness include psychological trauma, adverse childhood experiences, genetic predisposition, and personality traits. [7] [8] Correlations between mental disorders and substance use are also found to have a two way relationship, in that substance use can lead to the development of mental disorders and having mental disorders can lead to substance use/abuse.
Schizophrenia is not a particularly common mental health disorder in America, affecting just 1.2 percent of the population (around 3.2 million people), but its effects can be debilitating.
Studies suggest that people with schizophrenia have a reduced hippocampus volume, which is believed to be caused by a reduction of adult neurogenesis. Correspondingly, this phenomenon might be the underlying cause of many of the symptoms of the disease.
People with Schizophrenia appear to have a high rate of self-medication with nicotine; the therapeutic effect likely occurs through dopamine modulation by nicotinic acetylcholine receptors. However, there was controversy and conflicting findings over whether postmortem findings resulted from drug tolerance to chronic antipsychotic treatment.
Ads
related to: brains of people with schizophrenia are called the primary factors that contribute