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Chlortalidone is considered a first-line medication for treatment of high blood pressure. [2] Some recommend chlortalidone over hydrochlorothiazide. [1] [15] A meta-analysis of randomized controlled trials found that chlortalidone is more effective than hydrochlorothiazide for lowering blood pressure, while the two drugs have similar toxicity.
Chlorthalidone is the thiazide drug that is most strongly supported by the evidence as providing a mortality benefit; in the ALLHAT study, a chlorthalidone dose of 12.5 mg was used, with titration up to 25 mg for those subjects who did not achieve blood pressure control at 12.5 mg. Chlorthalidone has repeatedly been found to have a stronger ...
Several classes of medications, collectively referred to as antihypertensive medications, are available for treating hypertension. Use should take into account the person's cardiovascular risk (including risk of myocardial infarction and stroke), as well as blood pressure readings, in order to gain a more accurate picture of the person's risks. [2]
Chlorthalidone and hydrochlorothiazide are diuretics used to lower blood pressure. Learn more about the primary differences between these two medications.
Atenolol/chlorthalidone, also known as co-tenidone, is a combination medication used to treat high blood pressure. [2] [3] It is made up of atenolol, a beta-blocker and chlortalidone, a diuretic. [4] It is not recommended as an initial treatment but may be used in those who are taking atenolol and chlortalidone individually. [5] It is taken by ...
Refractory hypertension (RfHTN) is hypertension, a high blood pressure, that remains uncontrolled on maximal or near-maximal therapy, that includes the use of ≥5 antihypertensive agents of different classes. [1] Agents used include a long-acting thiazide-like diuretic (such as chlorthalidone) and spironolactone. [2]
The study concluded that major CHD events did not differ between initial use of chlorthalidone versus lisinopril or amlodipine. As a result, the Joint National Committee (7) guidelines of 2003, recommended the cheaper but equally effective diuretics as a first line treatment for hypertension. The study also confirmed the previously held views ...
This is because the condition is not yet well defined and makes it difficult for doctors to treat labile hypertension as medications are usually given for patients who have hypertension. Generally, doctors will suggest people to monitor and observe their blood pressure throughout the day, preferably for 24 hours, as commonly prescribed ...