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Selamectin, sold under the brand name Revolution, among others, is a topical parasiticide and anthelminthic used on dogs and cats. [2] It treats and prevents infections of heartworms , fleas , ear mites , sarcoptic mange (scabies), and certain types of ticks in dogs, and prevents heartworms, fleas, ear mites, hookworms , and roundworms in cats.
Cypermethrin is very toxic to cats which cannot tolerate the therapeutic doses for dogs. [6] This is associated with UGT1A6 deficiency in cats, the enzyme responsible for metabolizing cypermethrin. As a consequence, cypermethrin remains much longer in the cat's organs than in dogs or other mammals and can be fatal in large doses.
Permethrin is toxic to cats; however, it has little effect on dogs. [4] [49] [50] Many cats die after being given flea treatments intended for dogs, or by contact with dogs having recently been treated with permethrin. [51] In cats it may induce hyperexcitability, tremors, seizures, and death. [52]
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Cats are also more likely to have aberrant migration of heartworm larvae, resulting in infections in the brain or body cavities. [37] The infection rate in cats is 1–5% of that in dogs in endemic areas. [38] Both indoor and outdoor cats are infected. The mosquito vector is known to enter homes. [39]
Nitenpyram tablets, brand name Capstar, [17] are used to treat flea infestations in cats and dogs. [18] After oral administration of the tablet the drug is readily and quickly absorbed into the blood. If a flea bites the animal it will ingest with the blood the nitenpyram. The effect of nitenpyram can be observed half an hour after the ...
[30] [31] [3] The U.S. Food and Drug Administration has received reports of approximately 8500 animal deaths, including at least 1950 cats and 2200 dogs who have died after eating contaminated food, but have only confirmed 14 cases, in part because there is no centralized government database of animal sickness or death in the United States as ...
Diatomaceous earth can also be used as a home flea treatment in lieu of acetylcholinesterase inhibitory treatments or insecticides which carry with them a risk of poisoning for both humans and other animals. However, diatomaceous earth dust is harmful to pets and people when inhaled, requiring use of a dust mask to apply.