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Nitric oxide (NO) contributes to vessel homeostasis by inhibiting vascular smooth muscle contraction and growth, platelet aggregation, and leukocyte adhesion to the endothelium. Humans with atherosclerosis, diabetes, or hypertension often show impaired NO pathways. [50] Nitric oxide (NO) is a mediator of vasodilation in blood vessels.
The low blood pressure seen in those with sepsis is the result of various processes, including excessive production of chemicals that dilate blood vessels such as nitric oxide, a deficiency of chemicals that constrict blood vessels such as vasopressin, and activation of ATP-sensitive potassium channels. [41]
Nitric oxide reacts with transition metals to give complexes called metal nitrosyls. The most common bonding mode of nitric oxide is the terminal linear type (M−NO). [6] Alternatively, nitric oxide can serve as a one-electron pseudohalide. In such complexes, the M−N−O group is characterized by an angle between 120° and 140°.
Nitrox is known by many names: Enriched Air Nitrox, Oxygen Enriched Air, Nitrox, EANx or Safe Air. [ 3 ] [ 23 ] Since the word is a compound contraction or coined word and not an acronym, it should not be written in all upper case characters as "NITROX", [ 3 ] but may be initially capitalized when referring to specific mixtures such as Nitrox32 ...
Bloodstream infections (BSIs) are infections of blood caused by blood-borne pathogens. [1] The detection of microbes in the blood (most commonly accomplished by blood cultures [2]) is always abnormal. A bloodstream infection is different from sepsis, which is characterized by severe inflammatory or immune responses of the host organism to ...
Active viremia is caused by the replication of viruses which results in viruses being introduced into the bloodstream.Examples include the measles, in which primary viremia occurs in the epithelial lining of the respiratory tract before replicating and budding out of the cell basal layer (viral shedding), resulting in viruses budding into capillaries and blood vessels.
There are more than 200 different types of viruses that can cause a common cold, which is usually just a mild infection in the upper respiratory tract, hence the feeling of a sore throat, runny ...
Septic shock is a subclass of distributive shock, a condition in which abnormal distribution of blood flow in the smallest blood vessels results in inadequate blood supply to the body tissues, resulting in ischemia and organ dysfunction. Septic shock refers specifically to distributive shock due to sepsis as a result of infection. [14]