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  2. Trimethylamine N-oxide - Wikipedia

    en.wikipedia.org/wiki/Trimethylamine_N-oxide

    Trimethylamine N-oxide (TMAO) is an organic compound with the formula (CH 3) 3 NO. It is in the class of amine oxides. Although the anhydrous compound is known, trimethylamine N-oxide is usually encountered as the dihydrate. Both the anhydrous and hydrated materials are white, water-soluble solids.

  3. Trimethylaminuria - Wikipedia

    en.wikipedia.org/wiki/Trimethylaminuria

    Taking low doses of antibiotics such as neomycin and metronidazole [32] in order to reduce the amount of bacteria in the gut, although this is not recommended as a long term solution due to antibiotic resistance and other side effects. Using slightly acidic detergent and body washes with a pH between 5.5 and 6.5

  4. Flavin-containing monooxygenase 3 - Wikipedia

    en.wikipedia.org/wiki/Flavin-containing_mono...

    FMO3 is the primary enzyme in humans which catalyzes the N-oxidation of trimethylamine into trimethylamine N-oxide; [8] [10] FMO1 also does this, but to a much lesser extent than FMO3. [13] [14] Genetic deficiencies of the FMO3 enzyme cause primary trimethylaminuria, also known as "fish odor syndrome".

  5. Trimethylamine - Wikipedia

    en.wikipedia.org/wiki/Trimethylamine

    Trimethylamine (TMA) is an organic compound with the formula N(CH 3) 3.It is a trimethylated derivative of ammonia.TMA is widely used in industry. [5] [6] At higher concentrations it has an ammonia-like odor, and can cause necrosis of mucous membranes on contact. [7]

  6. Atherosclerosis - Wikipedia

    en.wikipedia.org/wiki/Atherosclerosis

    The microbiota – all the microorganisms in the body, can contribute to atherosclerosis in many ways: modulation of the immune system, changes in metabolism, processing of nutrients and production of certain metabolites that can get into blood circulation. [142] One such metabolite, produced by gut bacteria, is trimethylamine N-oxide (TMAO ...

  7. Trimethylamine N-oxide reductase - Wikipedia

    en.wikipedia.org/wiki/Trimethylamine_N-oxide...

    Trimethylamine N-oxide reductase has the EC number 1.7.2.3, and these components refer to the following enzyme classifications: EC 1 enzymes are oxidoreductase enzymes, where an oxidation reduction reaction occurs, and the substrate being oxidized is either an oxygen or hydrogen donor

  8. Human microbiome - Wikipedia

    en.wikipedia.org/wiki/Human_microbiome

    Graphic depicting the human skin microbiota, with relative prevalences of various classes of bacteria. The human microbiome is the aggregate of all microbiota that reside on or within human tissues and biofluids along with the corresponding anatomical sites in which they reside, [1] [2] including the gastrointestinal tract, skin, mammary glands, seminal fluid, uterus, ovarian follicles, lung ...

  9. Intestinal mucosal barrier - Wikipedia

    en.wikipedia.org/wiki/Intestinal_mucosal_barrier

    The commensal microbial species that inhabit the gut are considered by some to be part of the intestinal mucosal barrier. The gut microbiota can influence barrier function both directly, by stimulating epithelial cell proliferation and secretion of IL-8 , and indirectly by producing short-chain fatty acids , which are an important energy source ...