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Use of tPA in the United States in treatment of patients who are eligible for its use, have no contraindications, and arrival at the treating facility less than 3 hours after onset of symptoms, is reported to have doubled from 2003 to 2011. Use on patients with mild deficits, of nonwhite race/ethnicity, and oldest old age increased.
Alteplase, sold under the brand name Activase among others, is a biosynthetic form of human tissue-type plasminogen activator (t-PA). It is a thrombolytic medication used to treat acute ischemic stroke, acute ST-elevation myocardial infarction (a type of heart attack), pulmonary embolism associated with low blood pressure, and blocked central venous catheter. [5]
A cerebroprotectant (formerly known as a neuroprotectant) is a drug that is intended to protect the brain after the onset of acute ischemic stroke. [1] As stroke is the second largest cause of death worldwide and a leading cause of adult disability, over 150 drugs have been tested in clinical trials to provide cerebroprotection.
The National Institutes of Health Stroke Scale, or NIH Stroke Scale (NIHSS), is a tool used by healthcare providers to objectively quantify the impairment caused by a stroke and aid planning post-acute care disposition, though was intended to assess differences in interventions in clinical trials. The NIHSS was designed for the National ...
The Joint Commission defines a Primary Stroke Center as follows: "This program is designed for hospitals providing the critical elements to achieve long-term success in improving outcomes for stroke patients." [16] Primary stroke centers have "acute stroke teams" [13] as recommended by the Brain Attack Coalition. The centers should have a ...
Paraprofessional Healthcare Institute, Inc. (PHI) is a non-profit organization based in New York City that works to improve long-term services and supports for elders and individuals with disabilities, as well as improve the job quality of the direct-care workers who provide those services whether in people's homes or in nursing homes and other institutional facilities.
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The findings were published in the New England Medical Journal. Though safety has been established through previous clinical trials, there is ongoing debate about whether this is an effective treatment for ischemic stroke , and significant ongoing discussion between emergency physicians, neurologists and pharmacists about whether this treatment ...