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  2. Monroe Systems for Business - Wikipedia

    en.wikipedia.org/wiki/Monroe_Systems_for_Business

    Monroe Systems for Business is a provider of electric calculators, printers, and office accessories such as paper shredders to business clients. [1] Originally known as the Monroe Calculating Machine Company, it was founded in 1912 by Jay Randolph Monroe as a maker of adding machines and calculators based on a machine designed by Frank Stephen Baldwin.

  3. Trough level - Wikipedia

    en.wikipedia.org/wiki/Trough_level

    In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. [3] A trough level is contrasted with a "peak level" (C max), which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It is ...

  4. Vancomycin - Wikipedia

    en.wikipedia.org/wiki/Vancomycin

    In 1980s, vancomycin with a purity > 90% was available, and kidney toxicity defined by an increase in serum creatinine of at least 0.5 mg/dL occurred in only about 5% of patients. [36] But dosing guidelines from the 1980s until 2008 recommended vancomycin trough concentrations between 5 and 15 μg/mL. [37]

  5. Peak-to-trough ratio - Wikipedia

    en.wikipedia.org/wiki/Peak-to-trough_ratio

    Peak-to-trough ratio in pharmacokinetics is the ratio of peak (C max) and trough (C min) levels of a drug over its dosing interval (τ) at steady state.. Peak-to-trough ratio (PTR), also known as peak-to-trough variation or peak-to-trough fluctuation, is a parameter in pharmacokinetics which is defined as the ratio of C max (peak) concentration and C min (trough) concentration over a dosing ...

  6. Tide-predicting machine - Wikipedia

    en.wikipedia.org/wiki/Tide-predicting_machine

    The first tide predicting machine (TPM) was built in 1872 by the Légé Engineering Company. [11] A model of it was exhibited at the British Association meeting in 1873 [12] (for computing 8 tidal components), followed in 1875-76 by a machine on a slightly larger scale (for computing 10 tidal components), was designed by Sir William Thomson (who later became Lord Kelvin). [13]

  7. Friden, Inc. - Wikipedia

    en.wikipedia.org/wiki/Friden,_Inc.

    Friden Calculator Friden Flexowriter. In 1957, Friden purchased the Commercial Controls Corporation of Rochester, New York.This gave them the Flexowriter teleprinter, an electric typewriter capable of being used as part of unit record equipment developed in World War II for the Department of the Navy to automatically type "regret to inform you" letters to the survivors of fallen servicemen ...

  8. Marchant Calculating Machine Company - Wikipedia

    en.wikipedia.org/wiki/Marchant_Calculating...

    Marchant XLA calculator, based on Friden's design. The Marchant Calculating Machine Company was founded in 1911 by Rodney and Alfred Marchant in Oakland, California. The company built mechanical, and then electromechanical calculators which had a reputation for reliability. First models were similar to the Odhner arithmometer.

  9. Mechanical calculator - Wikipedia

    en.wikipedia.org/wiki/Mechanical_calculator

    For forty years the arithmometer was the only type of mechanical calculator available for sale until the industrial production of the more successful Odhner Arithmometer in 1890. [8] The comptometer, introduced in 1887, was the first machine to use a keyboard that consisted of columns of nine keys (from 1 to 9) for each digit.