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Muscle fatigue is when muscles that were initially generating a normal amount of force, then experience a declining ability to generate force. It can be a result of vigorous exercise, but abnormal fatigue may be caused by barriers to or interference with the different stages of muscle contraction. There are two main causes of muscle fatigue ...
Post-exertional malaise (PEM), sometimes referred to as post-exertional symptom exacerbation (PESE) [1] or post-exertional neuroimmune exhaustion (PENE), [2] is a worsening of symptoms that occurs after minimal exertion. It is the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and common in long COVID and fibromyalgia. [3][1] PEM is often severe enough to be ...
The 1994 research guidelines were proposed by the "International Chronic Fatigue Syndrome Study Group", led by the Centers for Disease Control and Prevention. [7][8] The criteria were described as the most widely used diagnostic criteria for CFS in 2007. [9] These criteria are sometimes called the "Fukuda definition" after the first author (Keiji Fukuda) of the publication. The 1994 CDC ...
Exertional rhabdomyolysis, the exercise-induced muscle breakdown that results in muscle pain/soreness, is commonly diagnosed using the urine myoglobin test accompanied by high levels of creatine kinase (CK). Myoglobin is the protein released into the bloodstream when skeletal muscle is broken down.
Other factors, such as muscle fatigue, inadequate stretching before exercise, and loss of body fluids can also trigger muscle cramps.
Cachexia (/ kəˈkɛksiə / [1]) is a complex syndrome associated with an underlying illness, causing ongoing muscle loss that is not entirely reversed with nutritional supplementation. A range of diseases can cause cachexia, most commonly cancer, congestive heart failure, chronic obstructive pulmonary disease, chronic kidney disease, and AIDS.
Rhabdomyolysis (shortened as rhabdo) is a condition in which damaged skeletal muscle breaks down rapidly, often due to high intensity exercise over a short period. [6][4][5] Symptoms may include muscle pains, weakness, vomiting, and confusion. [3][4] There may be tea-colored urine or an irregular heartbeat. [3][5] Some of the muscle breakdown products, such as the protein myoglobin, are ...
As a result of muscular hyperactivity, patients may present with muscle cramps, stiffness, myotonia -like symptoms (slow relaxation), associated walking difficulties, hyperhidrosis (excessive sweating), myokymia (quivering of a muscle), fasciculations (muscle twitching), fatigue, exercise intolerance, myoclonic jerks and other related symptoms.