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Hepatosplenomegaly (commonly abbreviated HSM) is the simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly).Hepatosplenomegaly can occur as the result of acute viral hepatitis, infectious mononucleosis, and histoplasmosis or it can be the sign of a serious and life-threatening lysosomal storage disease.
Ultrasound findings associated with congenital syphilis intrauterine infection (which are seen after 18 weeks gestation) include fetal hepatomegaly (enlarged liver)(seen in greater than 80% of cases), anemia (as measured by the peak systolic velocity of the middle cerebral artery)(33%), placentomegaly(an enlarged placenta)(27%), polyhydramnios ...
Abdominal ultrasonography of the liver, as a sagittal plane through the midclavicular line, with some standard measurements [2] Right lobe of the liver at the midclavicular line at ages 0 to 7 [16] Suspicion of hepatomegaly indicates a thorough medical history and physical examination, wherein the latter typically includes an increased liver span.
The spleen is a lymphatic organ, which means it is largely involved in the immune system and immune responses. When the spleen becomes enlarged, it is a strong sign of infection somewhere in the body and can be caused by inflammatory conditions such as rheumatoid arthritis.
Amyloidosis may also affect accessory digestive organs including the liver, and may present with jaundice, fatty stool, anorexia, fluid buildup in the abdomen, and spleen enlargement. [ 15 ] Accumulation of amyloid proteins in the liver can lead to elevations in serum aminotransferases and alkaline phosphatase , two biomarkers of liver injury ...
Autopsy: Cardiomegaly has been suggested when the heart weighs more than >399 grams in women and >449 grams in men. [8] Large intestine: Dilation Upper limit of normal range of diameter: [9] Cecum: 10.5 cm; Ascending colon: 7.0 cm; Transverse colon: 6.5 cm; descending colon and sigmoid colon: 6.8 cm; Rectum near rectal/sigmoid junction: 7.5 cm ...
The family of 70-year-old William Bryan claims surgeon Thomas Shaknovsky removed his liver and not his spleen during a procedure he did not survive.
Splenomegaly is an enlargement of the spleen. [1] The spleen usually lies in the left upper quadrant (LUQ) of the human abdomen.Splenomegaly is one of the four cardinal signs of hypersplenism which include: some reduction in number of circulating blood cells affecting granulocytes, erythrocytes or platelets in any combination; a compensatory proliferative response in the bone marrow; and the ...