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Megacolon is an abnormal dilation of the colon (also called the large intestine). [ 1 ] [ 2 ] This leads to hypertrophy of the colon. [ 2 ] The dilation is often accompanied by a paralysis of the peristaltic movements of the bowel.
High grade colitis may lead to severe complications, including perforation, toxic megacolon and death. Bleeding may occur due to colitis. Treatment with corticosteroids may lead to infectious complications, including: urinary tract infections, C. difficile infection, and pneumonia. [3]
CURB-65, also known as the CURB criteria, is a clinical prediction rule that has been validated for predicting mortality in community-acquired pneumonia [1] and infection of any site. [2] The CURB-65 is based on the earlier CURB score [3] and is recommended by the British Thoracic Society for the assessment of severity of pneumonia. [4]
Toxic megacolon is an acute form of colonic distension. [2] It is characterized by a very dilated colon ( megacolon ), accompanied by abdominal distension ( bloating ), and sometimes fever , abdominal pain , or shock .
Hospital acquired pneumonia is the second most common nosocomial infection (after urinary tract infections) and accounts for 15–20% of the total. [ 1 ] [ 2 ] [ 3 ] It is the most common cause of death among nosocomial infections and is the primary cause of death in intensive care units .
Because individuals with hospital-acquired pneumonia usually have underlying illnesses and are exposed to more dangerous bacteria, it tends to be more deadly than community-acquired pneumonia. Ventilator-associated pneumonia (VAP) is a subset of hospital-acquired pneumonia. VAP is pneumonia which occurs after at least 48 hours of intubation and ...
Chlamydia pneumoniae [1] is a species of Chlamydia, an obligate intracellular bacterium [2] that infects humans and is a major cause of pneumonia.It was known as the Taiwan acute respiratory agent (TWAR) from the names of the two original isolates – Taiwan (TW-183) and an acute respiratory isolate designated AR-39. [3]
CAP is common, affecting people of all ages, and its symptoms occur as a result of oxygen-absorbing areas of the lung filling with fluid. This inhibits lung function, causing dyspnea, fever, chest pains and cough. CAP, the most common type of pneumonia, is a leading cause of illness and death worldwide [citation needed].
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