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Also called a "dietary estrogen", it is a diverse group of naturally occurring nonsteroidal plant compounds that, because of its structural similarity to estradiol (17-β-estradiol), have the ability to cause estrogenic or antiestrogenic effects. [2]
Silybum marianum is a species of thistle.It has various common names including milk thistle, [1] blessed milkthistle, [2] Marian thistle, Mary thistle, Saint Mary's thistle, Mediterranean milk thistle, variegated thistle and Scotch thistle (not to be confused with Onopordum acanthium or Cirsium vulgare).
Milk thistle supplement sales in the U.S. reached $95 million in 2008, and its global market size skyrocketed to more than $1 billion by 2022, per one analysis.
Silibinin (), also known as silybin (both from Silybum, the generic name of the plant from which it is extracted), is the major active constituent of silymarin, a standardized extract of the milk thistle, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silychristin, silidianin, and others.
Xenoestrogens are a type of xenohormone that imitates estrogen.They can be either synthetic or natural chemical compounds.Synthetic xenoestrogens include some widely used industrial compounds, such as PCBs, BPA, and phthalates, which have estrogenic effects on a living organism even though they differ chemically from the estrogenic substances produced internally by the endocrine system of any ...
Milk thistle flowerhead Cirsium arizonicum, showing arachnoid cobwebbiness on stems and leaves, with ants attending aphids that might be taking advantage of the shelter. Thistle is the common name of a group of flowering plants characterized by leaves with sharp spikes on the margins, mostly in the family Asteraceae. Prickles can also occur all ...
Looking at data for about 60,000 women and 40,000 men, they found that women who drank 400 ml (13.53 oz) of milk a day had a 5% increase in the risk of having heat disease.
Signs of hyperestrogenism may include heightened levels of one or more of the estrogen sex hormones (usually estradiol and/or estrone), lowered levels of follicle-stimulating hormone and/or luteinizing hormone (due to suppression of the hypothalamic–pituitary–gonadal axis by estrogen), and lowered levels of androgens such as testosterone (generally only relevant to males). [1]
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