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In accordance with its lack of serotonin release and serotonin 5-HT 2B receptor agonism, phentermine appears to show no risk of primary pulmonary hypertension (PPH) or valvular heart disease (VHD) in humans. [32] [10] [27] Phentermine has been found to be active as an agonist of the rat and human trace amine-associated receptor 1 (TAAR1).
Mephentermine, sold under the brand name Wyamine among others, is a sympathomimetic medication which was previously used in the treatment of low blood pressure but is mostly no longer marketed. [6] [5] [4] [7] [8] It is used by injection into a vein or muscle, by inhalation, and by mouth. [4] [5]
Chlorphentermine, sold under the brand names Apsedon, Desopimon, and Lucofen, is a serotonergic appetite suppressant of the amphetamine family. Developed in 1962, it is the para-chloro derivative of the better-known appetite suppressant phentermine, which is still in current use.
The U.S. Food and Drug Administration (FDA) on Thursday approved a new type of prescription pain medication for adults to treat moderate to severe acute pain. The drug, called Journavx ...
"It has no sign of addiction, which makes it a hugely important new tool as we fight the opioid epidemic," he told Fox News Digital. In clinical trials, the non-opioid medication received high ...
Vertex Pharmaceuticals claimed in a press release that the medication can be used for many types of moderate-to-severe acute pain and has shown no evidence that it is addictive, like opioids.
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