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[3] [4] It was introduced as a sedative and medication for morning sickness without having been tested on pregnant women. [5] While initially deemed to be safe in pregnancy, concerns regarding birth defects were noted in 1961, and the medication was removed from the market in Europe that year. [3] [6]
Doxylamine is used in the combination drug pyridoxine/doxylamine to treat morning sickness (nausea and vomiting of pregnancy). [19] [20] [21] It is the only medication approved by the United States Food and Drug Administration for the treatment of morning sickness. [19] [20]
Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
Academics said they hope the discovery can lead to more effective treatments for the condition. Study finds why morning sickness is more severe for some pregnant women Skip to main content
Scientists are moving forward with researching cures for morning sickness, including testing drugs that block GDF15 from binding to its receptor in the brain, and exposing women to the hormone ...
Pipamazine (INN; trade names Mornidine, Mometine, Nausidol) is a drug of the phenothiazine class formerly used as an antiemetic.It is chemically related to chlorpromazine, but has negligible antipsychotic activity and produces few extrapyramidal side effects.
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