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Dexfenfluramine, marketed as dexfenfluramine hydrochloride under the name Redux, is a serotonergic anorectic drug: it reduces appetite by increasing the amount of extracellular serotonin in the brain. [ 3 ] It is the d- enantiomer of fenfluramine and is structurally similar to amphetamine, but lacks any psychologically stimulating effects.
Fenfluramine as a single drug was first introduced in the 1970s, but was not popular because it only temporarily reduced weight. [1] A 1984 study found a weight loss of 7.5 kg on average in 24 weeks, as compared to 4.4 kg under placebo. [4] It sold modestly until the 1990s, when it was combined with phentermine and heavily marketed.
Phentermine was marketed with fenfluramine or dexfenfluramine as a combination appetite suppressant and fat burning agent under the popular name fen-phen. [18] In 1997, after 24 cases of heart valve disease in fen-phen users, fenfluramine and dexfenfluramine were voluntarily taken off the market at the request of the FDA. [19]
Craigslist (stylized as craigslist) is a privately held American company [5] operating a classified advertisements website with sections devoted to jobs, housing, for sale, items wanted, services, community service, gigs, résumés, and discussion forums. Craig Newmark began the service in 1995 as an email distribution list to friends ...
With the support of the Los Angeles Times, a special LAPD Red Squad arrested so many strikers that the city's jails were soon filled. Broadway in the Historic Core 1917. Some 1,200 dock workers were corralled in a special stockade in Griffith Park. The Times wrote approvingly that "stockades and forced labor were a good remedy for IWW terrorism."
The Brockman Building is a 12-story Classical and Romanesque Revival building located in Downtown Los Angeles. Built in 1912, it was listed on the National Register of Historic Places in 2009. It is currently home to an 80 unit condo complex on the top 11 floors, and the restaurant Bottega Louie sits on the 1st floor.
Loaded 0%. The Philadelphia 76ers' season might be cursed. Shams Charania of ESPN reported Thursday that Tyrese Maxey, one of the Sixers' stars, is expected to miss a "couple of weeks" with a ...
Eskatrol was an amphetamine weight loss agent which was removed by the U.S. Food and Drug Administration (FDA) in 1981 after its manufacturer, [1] SmithKline & French (SKF), [2] failed to prove the therapeutic effectiveness (Emax) of the medication. At the time it was among the 200 most widely prescribed drugs in the United States.