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Aciclovir, also known as acyclovir, [4] is an antiviral medication. [5] It is primarily used for the treatment of herpes simplex virus infections, chickenpox , and shingles . [ 6 ] Other uses include prevention of cytomegalovirus infections following transplant and severe complications of Epstein–Barr virus infection.
Acyclovir (Aciclovir) Herpes Simplex, chickenpox, [2] varicella zoster virus: GSK: guanosine analogue RTI 1981 Adefovir: Hepatitis B [3] Gilead Sciences RTI 2002 , 2003 Amantadine: Influenza: Influenza A virus M2 proton channel antagonist Ampligen: Avian Influenza: Immunomodulatory double-stranded RNA: Amprenavir (Agenerase) HIV Protease ...
Several antiviral drugs are effective for treating herpes, including aciclovir (acyclovir), valaciclovir, famciclovir, and penciclovir. Aciclovir was the first discovered and is now available in generic. [65] Valaciclovir is also available as a generic [66] and is slightly more effective than aciclovir for reducing lesion healing time. [67]
Valaciclovir is a prodrug, an esterified version of aciclovir that has greater oral bioavailability (about 55%) than aciclovir. [1] It is converted by esterases to the active drug, aciclovir, and the amino acid valine via hepatic first-pass metabolism.
“I would like to investigate if the use of acyclovir, an anti-HSV medication, can be associated with any reduced cognitive issues due to acyclovir being used for treating viral encephalitis ...
The first successful antiviral, aciclovir, is a nucleoside analogue, and is effective against herpesvirus infections. The first antiviral drug to be approved for treating HIV, zidovudine (AZT), is also a nucleoside analogue.
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