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The response rate to sleep deprivation is generally agreed to be approximately 40-60%. A 2017 meta-analysis of 66 sleep studies with partial or total sleep deprivation in the treatment of depression found that the overall response rate (immediate relief of symptoms) to total sleep deprivation was 50.4% of individuals, and the response rate to partial sleep deprivation was 53.1% [3] In 2009, a ...
Molecular pathway of REM sleep deprivation-induced apoptosis in neurons. Sleep is necessary to repair cellular damage caused by reactive oxygen species and DNA damage. During long-term sleep deprivation, cellular damage aggregates up to a tipping point that triggers cellular degeneration and apoptosis.
Serotonin levels (in the form of 5-HT) have been shown to decrease during REM and NREM sleep, leading some researchers to believe that it is also involved in memory consolidation during sleep [citation needed]. Mice lacking the receptor gene for 5-HT engage in more REM sleep and perform better on spatial memory tasks. [48]
Experts explain what parasomnias are and treatment options.
Researchers from the University of California, Irvine have found that sleep apnea severity during the REM stage of sleep negatively impacts verbal memory. The risk is especially high in older ...
RBD is a sleep disorder characterized by the loss of normal skeletal muscle atonia during REM sleep and is associated with prominent motor activity and vivid dreaming. [6] [2] These dreams often involve screaming, shouting, laughing, crying, arm flailing, kicking, punching, choking, and jumping out of bed.
REM sleep is decreased during the first half of the sleep period and stage 1 sleep is increased in the second half of the sleep period. [5] Most antidepressants, in particular selective serotonin re-uptake inhibitors (SSRIs), such as citalopram and paroxetine, are potent inhibitors of REM sleep and may also cause a REM rebound on discontinuation.
Night terror, also called sleep terror, is a sleep disorder causing feelings of panic or dread and typically occurring during the first hours of stage 3–4 non-rapid eye movement (NREM) sleep [1] and lasting for 1 to 10 minutes. [2] It can last longer, especially in children. [2]