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Sildenafil Drug Interactions. A word on sildenafil drug interactions: Mixing antihypertensive prescription drugs (hypertension meds) with Viagra may cause low blood pressure. Since the medication ...
Sildenafil's brand name, Viagra, is widely recognized in popular culture, and the drug's association with treating erectile dysfunction has led to its recreational use. [33] The reasons behind such use include the belief that the drug increases libido, improves sexual performance, [ 33 ] or permanently increases penis size. [ 34 ]
After further trials, sildenafil citrate was approved by the Food and Drug Administration (FDA) in 1998 as the active ingredient in brand name Viagra, now a very well-known drug for ED. For most ...
Viagra’s main ingredient sildenafil is part of a class of drugs referred to as PDE5 inhibitors, which (unlike non-prescription supplements) are approved by the FDA for the treatment of ED.
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
Here’s a list of both the half-lives and duration of action for four of the most common ED drugs (PDE5 inhibitors): Viagra (or sildenafil) lasts three to five hours after it’s consumed.
Sildenafil (marketed as Viagra) was the first PDE5 inhibitor on the market. Originally created as a treatment for high blood pressure in 1989, it was found to have a secondary use as an effective PDE5 inhibitor, enabling men who use it to gain stronger erections after arousal. The FDA approved Viagra on March 27, 1998. [20]
Disadvantages: Chewable sildenafil and tadalafil have the same side effects as other PDE5 drugs. Chewable ED Meds Pros Our hard mints ED meds are a fresh take on old favorites.