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A Clarinase Repetab tablet contains 5 mg loratadine in the tablet coating and 120 mg pseudoephedrine sulfate equally distributed between the tablet coating and the barrier-coated core.
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [5] This includes allergic rhinitis (hay fever) and hives. [5] It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. [5]
pentoxyfylline – xanthine derivative used in as an antiinflammatory drug and in the prevention of endotoxemia; pergolide – dopamine receptor agonist used for the treatment of pituitary pars intermedia dysfunction in horses; phenobarbital – anti-convulsant used for seizures; phenylbutazone – nonsteroidal anti-inflammatory drug (NSAID)
Zyrtec-D, an example of combination therapy. Combination therapy with antihistamines. Antihistamines and decongestants can be used as a combination to treat nasal congestion, runny nose, and sneezing symptoms caused by common cold and hay fever. Some examples include: Pseudoephedrine + Loratadine (Claritin-D®) Pseudoephedrine + Cetirizine
Desloratadine sold under the brand name Clarinex among others, is a tricyclic H 1 inverse agonist that is used to treat allergies.It is an active metabolite of loratadine. [6]It was patented in 1984 and came into medical use in 2001. [7]
Pseudoephedrine is excreted through urine, and the concentration in urine of this drug shows a large inter-individual spread; that is, the same dose can give a vast difference in urine concentration for different individuals. [123]
JNJ-7777120 was a drug being developed by Johnson & Johnson Pharmaceutical Research & Development which acts as a potent and selective antagonist at the histamine H 4 receptor. [1] It has anti-inflammatory effects, [ 2 ] and has been demonstrated to be superior to traditional (H1) antihistamines in the treatment of pruritus (itching). [ 3 ]
[22] [23] The drug is also commonly described as possessing weak anticholinergic activity by acting as an antagonist of the muscarinic acetylcholine receptors. The dextrorotatory stereoisomer , dexchlorpheniramine , has been reported to possess K d values of 15 nM for the H 1 receptor and 1,300 nM for the muscarinic acetylcholine receptors in ...