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Hydrogels can be used as drug delivery vehicles, for transdermal application, ophthalmic drug delivery, [11] cancer treatment [12] or for wound dressing. [ 7 ] [ 13 ] As a type of water based formulation, hydrogels are generally less greasy and are easier to be removed than oil-based formulations like organogels. [ 6 ]
In order to attain high transgene expression, the electrostatic interaction between the gene and hydrogel polymer and the controlled release of the drug payload from the hydrogel is necessary. [36] Several gene therapy drugs used in hydrogel-based drug delivery systems include CRISPR/Cas9, [58] siRNA, [40] [59] and other RNA-based drugs. [59]
Pectin can also be used to stabilise acidic protein drinks, such as drinking yogurt, to improve the mouth-feel and the pulp stability in juice based drinks and as a fat substitute in baked goods. [36] [40] Typical levels of pectin used as a food additive are between 0.5 and 1.0% – this is about the same amount of pectin as in fresh fruit. [41]
Cross-linked Hydrogel. The reaction scheme below is a terpolymerization to form a cross-linked hydrogel. The reactant ammonium persulfate (APS) is used in polymer chemistry as a strong oxidizing agent that is often used along with tetramethylethylenediamine (TMEDA) to catalyze the polymerization when making polyacrylamide gels.
Specifically, hydrogels can be designed to release drugs or other agents in response to physical characteristics of the environment like temperature and pH. [12] The responsiveness of hydrogels is a result of their molecular structure and polymer networks. [12] Hydrogel nanoparticles have a promising future in the drug delivery field.
Ergonovine, also known as ergometrine and lysergic acid propanolamide is a medication used to cause contractions of the uterus to treat heavy vaginal bleeding after childbirth. [ 6 ] [ 1 ] It can be used either by mouth, by injection into a muscle , or injection into a vein . [ 6 ]
Etomidate will be classed as a controlled drug on 14 February 2025 by the Dangerous Drugs Ordinance (Cap. 134), which states that illegal possession or smoking, inhaling, ingesting and injecting space oil is liable to a maximum penalty of imprisonment of seven years and a fine of HK$1,000,000, while trafficking or illegal importing etomidate is ...
Feet of a baby born to a mother who had taken thalidomide while pregnant. In the late 1950s and early 1960s, the use of thalidomide in 46 countries was prescribed to women who were pregnant or who subsequently became pregnant, and consequently resulted in the "biggest anthropogenic medical disaster ever," with more than 10,000 children born with a range of severe deformities, such as ...