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[34] [35] [36] In premenopausal females, normal range of serum ferritin is between 12 and 150 [34] or 200 [35] ng/mL (330 or 440 pmol/L). [36] In those with hemochromatosis, the serum ferritin level correlates with the degree of iron overload. [7] Ferritin levels are usually monitored serially in those with hemochromatosis to assess response to ...
Ferritin genes are highly conserved between species. All vertebrate ferritin genes have three introns and four exons. [8] In human ferritin, introns are present between amino acid residues 14 and 15, 34 and 35, and 82 and 83; in addition, there are one to two hundred untranslated bases at either end of the combined exons. [9]
mistaken for U, meaning units; also has an ambiguous meaning; use "mL" or "millilitres" (1 cm 3 = 1 mL) cf. confer compare c.n. cras nocte: tomorrow night cochl. cochleare: spoonful cochl. ampl. cochleare amplum: an ample spoonful (a tablespoonful) cochl. infant. cochleare infantis: a small spoonful (a teaspoonful) cochl. mag. cochleare magnum
Iron can be stored in ferritin as ferric iron due to the ferroxidase activity of the ferritin heavy chain. [28] Dysfunctional ferritin may accumulate as hemosiderin, which can be problematic in cases of iron overload. [29] The ferritin storage iron pool is much larger than the labile iron pool, ranging in concentration from 0.7 mM to 3.6 mM. [25]
The normal range is 20 to 200 nanograms per milliliter (ng/mL) for men and 15 to 150 ng/mL for women. [8] Low levels (< 12 ng/mL) are specific for iron deficiency. [ 4 ] However, inflammatory and neoplastic disorders can cause ferritin levels to increase – this may be seen in cases of hepatitis, leukemia, Hodgkin lymphoma, and ...
Iron supplements are used to treat or prevent iron deficiency and iron-deficiency anemia; [8] parenteral irons can also be used to treat functional iron deficiency, where requirements for iron are greater than the body's ability to supply iron such as in inflammatory states.
Iron deficiency, or sideropenia, is the state in which a body lacks enough iron to supply its needs. Iron is present in all cells in the human body and has several vital functions, such as carrying oxygen to the tissues from the lungs as a key component of the hemoglobin protein, acting as a transport medium for electrons within the cells in the form of cytochromes, and facilitating oxygen ...
Recovery is reached faster and with fewer side effects than oral iron. [10] Intravenous iron is proven to be very effective for pregnant women with iron deficiency anaemia but not necessarily more effective than oral supplements for those with iron deficiency alone. [9] The type of iron supplement used depends on the patient's specific condition.
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