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There are several examples of immortalised cell lines, each with different properties. Most immortalised cell lines are classified by the cell type they originated from or are most similar to biologically 3T3 cells – a mouse fibroblast cell line derived from a spontaneous mutation in cultured mouse embryo tissue.
However, the cell line is appreciated to be N-type (neuronal), given its morphology and the ability to differentiate the cells into along the neuronal lineage (in contrast to the S-type SH-EP subcloned cell line, also derived from SK-N-SH). [4] Cells with short spiny neurite-like processes migrate out from these adherent clumps. SH-SY5Y cells ...
In cellular biology, stable cells are cells that multiply only when needed. They spend most of the time in the quiescent G 0 phase of the cell cycle but can be stimulated to enter the cell cycle when needed. Examples include the liver, the proximal tubules of the kidney and endocrine glands.
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Cellosaurus is an online knowledge base on cell lines, which attempts to document all cell lines used in biomedical research. [1] It is provided by the Swiss Institute of Bioinformatics (SIB). It is an ELIXIR Core Data Resource [ 2 ] [ 3 ] as well as an IRDiRC's Recognized Resource. [ 4 ]
Cell–cell interaction refers to the direct interactions between cell surfaces that play a crucial role in the development and function of multicellular organisms. These interactions allow cells to communicate with each other in response to changes in their microenvironment. This ability to send and receive signals is essential for the ...
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The S2 cells have been shown to grow up to 5.1×10 7 cells/ml in serum free medium [3] and above 10 7 cells/ml in basal media such as that used in Schneider's experiments. [4] ExpreS2ion Biotechnologies have shown a cell concentration of up 7.0x10 7 cell/ml. [5] S2 cells are often used for expression of heterologous proteins and can be used for ...