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Chlortalidone is considered a first-line medication for treatment of high blood pressure. [2] Some recommend chlortalidone over hydrochlorothiazide. [1] [15] A meta-analysis of randomized controlled trials found that chlortalidone is more effective than hydrochlorothiazide for lowering blood pressure, while the two drugs have similar toxicity.
"Chlortalidone has a higher risk of side effects than hydrochlorothiazide." [1] Quote = However, chlorthalidone use is more frequently associated with adverse metabolic effects, particularly hypokalemia and hyponatremia, compared with HCTZ. Doc James (talk · contribs · email) 09:34, 2 November 2019 (UTC) Agreed. That ref is clear.
The thiazide-like diuretics (indapamide and chlorthalidone) reduce risk of major cardiovascular events and heart failure in hypertensive patients compared with hydrochlorothiazide with a comparable incidence of adverse events. [5] Both thiazide diuretics and thiazide-like diuretics are effective in reducing risk of stroke.
Critics have long argued that while studying the effects of Red Dye No. 3 in humans poses ethical and scientific challenges, its ban in cosmetics should have logically extended to the food supply.
LONDON (AP) — Advanced artificial intelligence systems have the potential to create extreme new risks, such as fueling widespread job losses, enabling terrorism or running amok, experts said in a first-of-its-kind international report Wednesday cataloging the range of dangers posed by the technology.
Humans can smell chlorine gas at ranges from 0.1–0.3 ppm. According to a review from 2010: "At 1–3 ppm, there is mild mucous membrane irritation that can usually be tolerated for about an hour. At 5–15 ppm, there is moderate mucous membrane irritation. At 30 ppm and beyond, there is immediate chest pain, shortness of breath, and cough.
When ants bite humans, it grabs the skin and also sprays a compound called formic acid, Frye explains. Ant bites tend to be small, swollen bumps that appear in clusters, Kassouf says.
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