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Chlortalidone, also known as chlorthalidone, is a thiazide-like diuretic drug [1] used to treat high blood pressure, swelling (such as occurs in heart failure, liver failure, and nephrotic syndrome), diabetes insipidus, and renal tubular acidosis.
Chlorthalidone is the thiazide drug that is most strongly supported by the evidence as providing a mortality benefit; in the ALLHAT study, a chlorthalidone dose of 12.5 mg was used, with titration up to 25 mg for those subjects who did not achieve blood pressure control at 12.5 mg. Chlorthalidone has repeatedly been found to have a stronger ...
Uncontrolled high blood pressure can result in a greater risk for cognitive decline or dementia as well as cardiovascular disease. ... Doctors will often recommend a low dose of ... chlorthalidone ...
Low-dose thiazides are tolerated as well as the other classes of medications for hypertension, including ACE inhibitors, beta blockers and calcium channel blockers. [9] In general, the thiazides and thiazide-like diuretics reduce the risk of death, stroke, heart attack , and heart failure due to hypertension.
Antihypertensive agents comprise multiple classes of compounds that are intended to manage hypertension (high blood pressure). Antihypertensive therapy aims to maintain a blood pressure goal of <140/90 mmHg in all patients, as well as to prevent the progression or recurrence of cardiovascular diseases (CVD) in hypertensive patients with established CVD. [2]
A 2012 Cochrane review found that medications for mild hypertension did not reduce the risk of death, stroke, or cardiovascular disease, but did cause side effects in 1 of every 12 people. [ 8 ] [ 10 ] A second review that looked at higher-risk people (mostly diabetics whose blood pressure was difficult to control) found the medication ...
Atenolol/chlorthalidone, also known as co-tenidone, is a combination medication used to treat high blood pressure. [2] [3] It is made up of atenolol, a beta-blocker and chlortalidone, a diuretic. [4] It is not recommended as an initial treatment but may be used in those who are taking atenolol and chlortalidone individually. [5] It is taken by ...
Prepare for potential side effects. Taking metformin may cause unpleasant side effects like diarrhea, nausea, upset stomach and, in rare cases, lactic acidosis. Don’t double up on metformin if ...
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