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This makes aspirin different from other NSAIDs (such as diclofenac and ibuprofen), which are reversible inhibitors; aspirin creates an allosteric change in the structure of the COX enzyme. [2] However, other effects of aspirin, such as uncoupling oxidative phosphorylation in mitochondria, [3] and the modulation of signaling through NF-κB, are ...
Callyspongia (Cladochalina) aculeata, commonly known as the branching vase sponge is a species of sea sponge in the family Callyspongiidae. [1] Poriferans are typically characterized by ostia, pores that filter out plankton, with an osculum as the opening which water leaves through, and choanocytes trap food particles.
For some people, aspirin does not have as strong an effect on platelets as for others, an effect known as aspirin-resistance or insensitivity. One study has suggested women are more likely to be resistant than men, [158] and a different, aggregate study of 2,930 people found 28% were resistant. [159]
Guiding principles for more ethical use of animals in testing are the Three Rs first described by Russell and Burch in 1959. [41] These principles are now followed in many testing establishments worldwide. Replacement refers to the preferred use of non-animal methods over animal methods whenever it is possible to achieve the same scientific aim.
Lysine acetylsalicylate, also known as aspirin DL-lysine or lysine aspirin, is a more soluble form of acetylsalicylic acid (aspirin). As with aspirin itself, it is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory, antithrombotic and antipyretic properties. [ 1 ]
Fish fulfill several criteria proposed as indicating that non-human animals experience pain. These fulfilled criteria include a suitable nervous system and sensory receptors, opioid receptors and reduced responses to noxious stimuli when given analgesics and local anaesthetics, physiological changes to noxious stimuli, displaying protective motor reactions, exhibiting avoidance learning and ...
Ciona intestinalis (sometimes known by the common name of vase tunicate) is an ascidian (sea squirt), a tunicate with very soft tunic. Its Latin name literally means "pillar of intestines", referring to the fact that its body is a soft, translucent column-like structure, resembling a mass of intestines sprouting from a rock. [ 1 ]
Vase life is a term used by the floristry industry that describes the period during which a cut flower or cut foliage retains its appearance in a vase. This is a major consideration in identifying plant species suitable for use in floristry, as plants with a long vase life are far more desirable than those with a short vase life.