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Oxidative stress mechanisms in tissue injury. Free radical toxicity induced by xenobiotics and the subsequent detoxification by cellular enzymes (termination).. Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. [1]
XthA (exonuclease III, a DNA repair enzyme) and KatE (catalase) are known to play important roles in the defense against oxidative stress but KatF regulon genes are not induced by oxidative stress. [2] There is an overlap between oxidative stress response and other regulatory networks like heat shock response, SOS response.
Pro-oxidants are chemicals that induce oxidative stress, either by generating reactive oxygen species or by inhibiting antioxidant systems. [1] The oxidative stress produced by these chemicals can damage cells and tissues, for example, an overdose of the analgesic paracetamol (acetaminophen) can fatally damage the liver, partly through its production of reactive oxygen species.
This is a list of major and frequently observed neurological disorders (e.g., Alzheimer's disease), symptoms (e.g., back pain), signs (e.g., aphasia) and syndromes (e.g., Aicardi syndrome). There is disagreement over the definitions and criteria used to delineate various disorders and whether some of these conditions should be classified as ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 17 February 2025. The following is a list of mental disorders as defined at any point by the Diagnostic and Statistical Manual of Mental Disorders (DSM) or the International Classification of Diseases (ICD). A mental disorder, also known as a mental illness, mental health condition, or psychiatric ...
Printable version; In other projects ... Please improve this article by adding one in your own words. ... List of inflammatory disorders.
A medical condition is a broad term that includes all diseases and disorders. A disease is an abnormal condition affecting the body of an organism. A disorder is a functional abnormality or disturbance. Lists of animal diseases; List of autoimmune diseases; List of cancer types; List of childhood diseases and disorders; List of endocrine ...
This is a list of mental disorders as defined in the DSM-IV, the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders.Published by the American Psychiatry Association (APA), it was released in May 1994, [1] superseding the DSM-III-R (1987).