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Dorzolamide/timolol, sold under the brand name Cosopt among others, is a medication used to treat high pressure inside the eye including glaucoma. [3] [5] [6] It is a combination of dorzolamide hydrochloride and timolol maleate. [3] It may be used when a beta blocker, like timolol, is not sufficient alone. [7] It is used as an eye drop. [3]
No formal interaction studies have been done with bimatoprost/timolol eye drops. As timolol (in tablet form) can be used to lower blood pressure and heart rhythm, it might add to the effect of other antihypertensive (pressure lowering) drugs. Also, drugs that block the liver enzyme CYP2D6 may increase the effects of timolol. [4]
The IOP is higher during sleep. Efficacy of timolol in lowering IOP during the sleep period may be limited. [16] [17] [18] It is a 5–10× more potent beta blocker than propranolol. Timolol is light-sensitive; it is usually preserved with 0.01% benzalkonium chloride (BAC), but also comes BAC-free.
Alcon's (ALC) new preservative-free solution for patients with dry eye symptoms is the latest addition to its leading global artificial tear brand Systane.
It is also available as the combination dorzolamide/timolol. [3] [4] Common side effects include eye discomfort, eye redness, taste changes, and blurry vision. [3] Serious side effects include Steven Johnson syndrome. [3] Those allergic to sulfonamides may be allergic to dorzolamide. [3] [5] Use is not recommended in pregnancy or breastfeeding. [5]
Bimatoprost is used for the treatment of open-angle glaucoma and ocular hypertension in adults, either alone or in combination with a beta blocker, typically timolol. [ 5 ] [ 4 ] [ 10 ] Studies have shown bimatoprost to be more effective than timolol in reduction of intraocular pressure (IOP) and at least as effective as the prostaglandin ...
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261