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Reflux nephropathy is kidney damage (nephropathy) due to urine flowing backward (reflux) from the bladder toward the kidneys; the latter is called vesicoureteral reflux (VUR). Longstanding VUR can result in small and scarred kidneys during the first five years of life in affected children.
Glomerulosclerosis is the hardening of the glomeruli in the kidney. It is a general term to describe scarring of the kidneys' tiny blood vessels, the glomeruli, the functional units in the kidney that filter urea from the blood. Proteinuria (large amounts of protein in the urine) is one of the signs of glomerulosclerosis. Scarring disturbs the ...
Reflux also increases risk of acute bladder and kidney infections, so testing for reflux may be performed after a child has one or more infections. In infants, the signs and symptoms of a urinary tract infection may include only fever and lethargy , with poor appetite and sometimes foul-smelling urine, while older children typically present ...
Focal segmental glomerulosclerosis (FSGS) is a histopathologic finding of scarring of glomeruli and damage to renal podocytes. [ 2 ] [ 3 ] This process damages the filtration function of the kidney, resulting in protein presence in the urine due to protein loss. [ 3 ]
The scarring of the small blood vessels, called capillary sclerosis, is the initial lesion of analgesic nephropathy. [7] Found in the renal pelvis, ureter, and capillaries supplying the nephrons, capillary sclerosis is thought to lead to renal papillary necrosis and, in turn, chronic interstitial nephritis.
Acute tubular necrosis (ATN) is a medical condition involving the death of tubular epithelial cells that form the renal tubules of the kidneys.Because necrosis is often not present, the term acute tubular injury (ATI) is preferred by pathologists over the older name acute tubular necrosis (ATN). [1]
Nephritic syndrome is a syndrome comprising signs of nephritis, which is kidney disease involving inflammation.It often occurs in the glomerulus, where it is called glomerulonephritis.
Membranous glomerulonephritis (MGN) is a slowly progressive disease of the kidney affecting mostly people between ages of 30 and 50 years, usually white people (i.e., those of European, Middle Eastern, or North African ancestry.) [citation needed].