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Lithium carbonate can induce a 1–2 kg of weight gain. [70] In addition to tremors, lithium treatment appears to be a risk factor for development of parkinsonism-like symptoms, although the causal mechanism remains unknown. [71] Most side effects of lithium are dose-dependent. The lowest effective dose is used to limit the risk of side effects.
Lithium toxicity can be mistaken for other syndromes associated with antipsychotic use, such as serotonin syndrome because lithium increases serotonin metabolites in the cerebrospinal fluid. [14] There are several drug interactions with lithium. Interactions can occur from typical antipsychotics or atypical antipsychotics. In particular ...
Potential side effects from lithium include gastrointestinal upset, tremor, sedation, excessive thirst, frequent urination, cognitive problems, impaired motor coordination, hair loss, and acne. [3] Excessive levels of lithium can be harmful to the kidneys, and increase the risk of side effects in general.
The most common side effects are lethargy and weight gain. The less common side effects of using lithium are blurred vision, a slight tremble in the hands, and a feeling of being mildly ill. In general, these side effects occur in the first few weeks after commencing lithium treatment. These symptoms can often be improved by lowering the dose. [4]
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Lithium carbonate is an important industrial chemical. Its main use is as a precursor to compounds used in lithium-ion batteries. Glasses derived from lithium carbonate are useful in ovenware. Lithium carbonate is a common ingredient in both low-fire and high-fire ceramic glaze. It forms low-melting fluxes with silica and other materials.
For antihypertensive drugs, diuretics causes sodium loss, which reduces the renal clearance of lithium, while symptoms of lithium toxicity have also been reported when methyldopa is used together with lithium. [15] NSAIDs have similar effects to diuretics drugs, which is decreasing the renal clearance of lithium.
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