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A 100 mg Rimadyl tablet approximately 19 mm (0.75 in) wide by 8.6 mm (0.34 in) thick, as sold in the USA. Carprofen is a nonsteroidal anti-inflammatory drug (NSAID) of the carbazole and propionic acid class that was previously for use in humans and animals but is now only available to veterinarians for prescribing as a supportive treatment for various conditions in animals. [1]
Brodifacoum is a highly lethal 4-hydroxycoumarin vitamin K antagonist anticoagulant poison.In recent years, it has become one of the world's most widely used pesticides.It is typically used as a rodenticide, but is also used to control larger pests such as possums.
Anticoagulants are defined as chronic (death occurs one to two weeks after ingestion of the lethal dose, rarely sooner), single-dose (second generation) or multiple-dose (first generation) rodenticides, acting by effective blocking of the vitamin-K cycle, resulting in inability to produce essential blood-clotting factors—mainly coagulation factors II (prothrombin) and VII (proconvertin).
Adverse effects occur in fewer than 1% of patients and include muscle weakness, headache, arterial hypotension, nausea, vomiting, dyspepsia, and dry mouth. All effects are reversible. [3] [4] Allergic reactions occur in fewer than 0.1% of patient and include skin rash, hives, Quincke's edema, and in some cases anaphylactic shock. [3] [7] [8] [9]
d-CON is an America brand of rodent control products, which is distributed and owned in the United States by the UK-based consumer goods company Reckitt.. The brand includes traps and baits for use around the home for trapping and killing some rats and mice.
Atipamezole, sold under the brand name Antisedan among others, is a synthetic α 2 adrenergic receptor antagonist used for the reversal of the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs. Its reversal effect works by competing with the sedative for α 2-adrenergic receptors and displacing them.
The drug is FDA-approved for prevention of heartworm in dogs and cats, [4] although it is less potent against heartworms than ivermectin. [citation needed] The substance is often combined with other parasiticides to achieve a broader spectrum of action. Such products include: [citation needed] Milbemax and Interceptor Plus (with praziquantel)
In dogs, sheep, horses, and cattle, the half-life is very short: only 1.21– 5.97 minutes. Complete elimination of the drug can take up to 23 minutes in sheep and up to 49 minutes in horses. [1] [3] In young rats the half-life is one hour. [18] Xylazine has a large volume of distribution of V d = 1.9 – 2.5 for horses, cattle, sheep, and dogs ...