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A bottle of Excedrin with some of the caplets. Excedrin is an over-the-counter headache pain reliever, typically in the form of tablets or caplets. It contains paracetamol, aspirin and caffeine. It was manufactured by Bristol-Myers Squibb until it was purchased by Novartis in July 2005 along with other products from BMS's over-the-counter business.
The medication paracetamol (/ ˌ p ær ə ˈ s iː t ə m ɒ l / or / ˌ p ær ə ˈ s ɛ t ə m ɒ l /), also known as acetaminophen (/ ə ˌ s iː t ə ˈ m ɪ n ə f ɪ n / ⓘ), is sold around the world under a number of different brand names. Common brand names include Tylenol, Excedrin, Calpol, and Panadol.
The combination was first introduced as the name Trigesic, as the formula of 125 mg paracetamol, 230 mg aspirin, and 30 mg caffeine, in July 1950 by Squibb, which is now Bristol Myers Squibb, but was recalled in the following year due to several reports that the drug might cause blood dyscrasia. [5]
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Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedy PainAid. It was also an ingredient in the over-the-counter pain remedy BC Powder but was removed from the formulation in 2009, and Excedrin used the ingredient from 1960 to 1980 in conjunction with aspirin , acetaminophen , and caffeine .
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