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2. Nicotine dependence - Wikipedia

   en.wikipedia.org/wiki/Nicotine_dependence

   A National Institute on Drug Abuse video entitled Anyone Can Become Addicted to Drugs. [21]Nicotine dependence is defined as a neurobiological adaptation to repeated drug exposure that is manifested by highly controlled or compulsive use, the development of tolerance, experiencing withdrawal symptoms upon cessation including cravings, and an inability to quit despite harmful effects. [9]

3. Nicorette - Wikipedia

   en.wikipedia.org/wiki/Nicorette

   The Nicorette Patch was introduced to the market in 1991 [34] and the nasal spray in 1994. [35] In 1996, the FDA approved the switch of Nicorette gum and the NicoDerm CQ transdermal nicotine patch to over-the-counter status in the US. [36] The Nicorette inhaler was launched in 1996 [35] and Nicorette Microtab (sublingual tablets) in 1999. [37]

4. Nicotine - Wikipedia

   en.wikipedia.org/wiki/Nicotine

   The effects of nicotine can be differentiated between short-term and long-term use. Short-term nicotine use, such as that associated with nicotine replacement therapy (NRT) for smoking cessation, appears to pose little cardiovascular risk, even for patients with known cardiovascular conditions. In contrast, longer-term nicotine use may not ...

5. The 3 most effective ways to stop smoking, according to ... - AOL

   www.aol.com/3-most-effective-ways-stop-160000655...

   A new review of existing studies pinpoints the most effective strategies that can help a person quit smoking. These include a common anti-nicotine drug, a plant-based drug, and nicotine e-cigarettes.

6. Tobacco and life insurance: Here’s what you should know - AOL

   www.aol.com/finance/tobacco-life-insurance-know...

   Hair test: Hair tests are reliable for long-term detection, showing nicotine use for one to three months. In some cases, nicotine can be detected for up to 12 months.

7. Effects of nicotine on human brain development - Wikipedia

   en.wikipedia.org/wiki/Effects_of_nicotine_on...

   The health effects of long-term nicotine use is unknown. [18] It may be decades before the long-term health effects of nicotine e-cigarette aerosol inhalation is known. [19] Short-term nicotine use excites the autonomic ganglia nerves and autonomic nerves, but chronic use seems to induce negative effects on endothelial cells. [20]