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A more focused functional genomics approach might test the function of all variants of one gene and quantify the effects of mutants by using sequencing as a readout of activity. Together these measurement modalities endeavor to quantitate the various biological processes and improve our understanding of gene and protein functions and interactions.
The Critical Assessment of Functional Annotation (CAFA) is an experiment designed to provide a large-scale assessment of computational methods dedicated to predicting protein function. [1] Different algorithms are evaluated by their ability to predict the Gene Ontology (GO) terms in the categories of Molecular Function , Biological Process ...
Rapid automatized naming (RAN) is a task that measures how quickly individuals can name aloud objects, pictures, colors, or symbols (letters or digits). Variations in rapid automatized naming time in children provide a strong predictor of their later ability to read, and is independent from other predictors such as phonological awareness, verbal IQ, and existing reading skills. [1]
The key issue then is the translation of these newly identified genetic variants (from Copy Number Variant studies, candidate gene sequencing and high throughput sequencing technologies) into an intervention for patients with neurogenomic disorders. One aspect will be if the neurological disorder are medically actionable (i.e. is there a simple ...
For enzymes, predictions of specific functions are especially difficult, as they only need a few key residues in their active site, hence very different sequences can have very similar activities. By contrast, even with sequence identity of 70% or greater, 10% of any pair of enzymes have different substrates; and differences in the actual ...
Enjoy a classic game of Hearts and watch out for the Queen of Spades!
Small groups—students work on assignments in groups of three or four. Workshops—students perform various tasks simultaneously. Workshop activities must be tailored to the lesson plan. Independent work—students complete assignments individually. Peer learning—students work together, face to face, so they can learn from one another.
Typically, dementia is associated with classic symptoms like confusion and memory loss. But new research finds that there could be a less obvious risk factor out there: your cholesterol levels ...
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