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Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, [7] is a contagious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. [1] Tuberculosis generally affects the lungs, but it can also affect other parts of the body. [1]
In many African countries, 30–60% of all new TB cases occur in people with HIV, and TB is the leading cause of death globally for HIV-infected people." [ 10 ] Reactivation
Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [ 1 ] [ 2 ] First discovered in 1882 by Robert Koch , M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid .
Ultimately, though, TB can avoid the mucus traps and make its way to the deep airways and alveoli where we have macrophages which eat up foreign cells, digest, and destroy them. With TB, they recognize foreign proteins on their cell surface, and phagocytize them, or essentially package them into a space called a phagosome.
Charlotte Brontë's death in 1855 was stated at the time as having been due to tuberculosis, but there is some controversy over this today. Clarissa Brooks, poet, died of tuberculosis in 1927; Charles Brockden Brown; Charles Farrar Browne; Elizabeth Barrett Browning, poet, died of tuberculosis in 1861; Jean de Brunhoff
[9] WHO's Global TB Programme Director, Dr. Arata Kochi, promised that, "Today the situation of the global TB epidemic is about to change, because we have made a breakthrough. It is the breakthrough of health management systems that makes it possible to control TB not only in wealthy countries, but in all parts of the developing world, where 95 ...
These people can in turn infect other people with MDR-TB. [5] [8] MDR-TB caused an estimated 600,000 new TB cases and 240,000 deaths in 2016 and MDR-TB accounts for 4.1% of all new TB cases and 19% of previously treated cases worldwide. [13] Globally, most MDR-TB cases occur in South America, Southern Africa, India, China, and the former Soviet ...
This is a bibliography of tuberculosis (TB), an infectious disease that generally affects the lungs. As of 2018, the World Health Organization estimated that 25% of the world's population was infected with the latent form of the disease. In its active form, it is one of the top 10 causes of death worldwide. [1]